37951-15-8

Basic information

• Product Name: 4-phenoxy-1,2-benzenedicarboxylic acid
• Synonyms: 4-phenoxy-1,2-benzenedicarboxylic acid
• CAS NO: 37951-15-8
• Molecular Weight: 258.23
• Mol File: 37951-15-8.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 4-phenoxy-1,2-benzenedicarboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-phenoxy-1,2-benzenedicarboxylic acid(37951-15-8)
• EPA Substance Registry System: 4-phenoxy-1,2-benzenedicarboxylic acid(37951-15-8)

Safety Data

• Hazardous Substances Data: 37951-15-8(Hazardous Substances Data)

Usage

General Description

4-phenoxy-1,2-benzenedicarboxylic acid, also known as Phenylphthalic acid, is a chemical compound with the molecular formula C14H10O5. It is a white, powdery solid that is insoluble in water but soluble in organic solvents. 4-phenoxy-1,2-benzenedicarboxylic acid is often used as a building block in the synthesis of various pharmaceuticals, dyes, and polymers. It exhibits some potential for biological activity and has been studied for its potential use in anti-cancer and anti-inflammatory drugs. Additionally, it is also used as an intermediate in the production of fragrances and as a plasticizer in the manufacturing of plastics and resins.

Upstream product

• 31643-49-9 4-Nitrophthalonitrile 
• 108-95-2 phenol 
• 38791-62-7 4-phenoxyphthalonitrile 
• 52509-74-7 3,4-dimethylphenyl phenyl ether 

Downstream Products

• 123466-48-8 5-phenoxy-isoindoline-1,3-dione-1,3-diimine 
• 808118-40-3 [(4-hydroxy-1-methyl-7-phenoxy-isoquinoline-3-carbonyl)-amino]-acetic acid 
• 1421312-31-3 C₁₈H₁₃NO₆ 
• 1421312-32-4 C₁₇H₁₃NO₅ 
• 1421312-33-5 methyl 4-hydroxy-1-chloro-7-phenoxyisoquinoline-3-carboxylate 
• 1421312-34-6 4-hydroxy-1-methyl-7-phenoxyisoquinolinyl-3-carboxylic acid methyl ester 
• 1421312-35-7 4-hydroxy-1-methyl-7-phenoxy-3-isoquinolinecarboxylic acid 
• 1421312-36-8 [(4-hydroxy-1-methyl-7-phenoxy-isoquinoline-3-carbonyl)amino]acetic acid methyl ester 
• 38791-58-1 4-phenoxyphthalic acid diethyl ester 
• 21345-01-7 4-phenoxyphthalic anhydride 

Relevant articles and documents

PROCESS FOR THE PREPARATION OF ROXADUSTAT AND ITS INTERMEDIATES

The present invention provides the process for the preparation of Roxadustat and its intermediates. Another aspect of the present invention provides a process for preparation of ethyl-5-(2-butoxycarbonyl)-4-phenoxyphenyl) oxazole-4-carboxylate of the formula (X) and its use in the preparation of Roxadustat. Another aspect of the present invention provides a process for the preparation of ethyl-4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxylate of the formula (XIII) and its use in the preparation of Roxadustat.

CRYSTAL TYPES OF COMPOUNDS INHIBITING ACTIVITY OF PROLYL HYDROXYLASE AND USE THEREOF

The invention relates to crystal types of compound shown as structural formula I, methods of preparing the compound, intermediate, pharmaceutical composition, and use of treating disease or pharmaceutical preparations for treating disease.

POLYMORPHIC FORMS OF COMPOUNDS AS PROLYL HYDROXYLASE INHIBITOR, AND USES THEREOF

The present invention relates to the polymorphic forms of the compound of Formula (I), preparation thereof including the preparation of intermediates and pharmaceutical compositions, and use of a polymorph above in the treatment of a disease, a disorder o