3937-94-8 Usage
General Description
(4-NITROPHENYL)SULFONYL]ACETIC ACID, also known as NSAA, is a chemical compound with the molecular formula C8H7NO6S. It is a sulfonamide derivative that has been used in various pharmaceutical and organic synthesis applications. NSAA is a potent inhibitor of the enzyme calcineurin and has been studied for its potential therapeutic effects in the treatment of cancer, autoimmune diseases, and other conditions. It has also been explored for its anti-inflammatory and analgesic properties. NSAA has been the subject of research and development for its potential as a drug candidate in various medical applications.
Check Digit Verification of cas no
The CAS Registry Mumber 3937-94-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,9,3 and 7 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 3937-94:
(6*3)+(5*9)+(4*3)+(3*7)+(2*9)+(1*4)=118
118 % 10 = 8
So 3937-94-8 is a valid CAS Registry Number.
InChI:InChI=1/C8H7NO6S/c10-8(11)5-16(14,15)7-3-1-6(2-4-7)9(12)13/h1-4H,5H2,(H,10,11)/p-1
3937-94-8Relevant articles and documents
3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF
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Paragraph 00435, (2017/10/06)
The present invention provides compounds, compositions thereof, and methods of using the same.
SYNTHESIS OF ORGANOSULFONYLACETIC ACID
Mirskova, A.N.,Kryukova, Yu.I.,Levkovskaya, G.G.,Guseva, S.A.,Voronkov, M.G.
, p. 545 - 550 (2007/10/02)
Alkylsulfonylacetic acids and their esters were obtained by the alcoholysis of alkyl β,β-dichlorovinyl sulfones and the oxidation of alkylthioacetic acids.Arylsulfonylacetic acids were synthesized by the reaction of sodium arenesulfinates with monochloroacetic acid.The optimum conditions for the reaction were obtained.Arylsulfonylacetic esters were obtained by the reaction of monochloroacetic esters with sodium arenesulfinate in DMFA, and their hydrolysis led to the corresponding acids with yields of 65-98percent.Dichloroacetic estersreacts with arenesulfinates, forming di(arylsulfonyl)acetic esters.
