4362-89-4Relevant articles and documents
1,1-Diaminoazines as organocatalysts in phospha-Michael addition reactions
Bharatam, Prasad V.,Chourasiya, Sumit S.,Kathuria, Deepika,Wani, Aabid A.
supporting information, p. 11717 - 11720 (2021/11/12)
1,1-Diaminoazines can act as effective organocatalysts for the formation of phosphorus-carbon bonds between biphenylphosphine oxide and an activated alkene (Michael acceptor). These catalysts provide the P-C adducts at a faster rate and with relatively be
New furin inhibitors based on weakly basic amidinohydrazones
Sielaff, Frank,Than, Manuel E.,Bevec, Dorian,Lindberg, Iris,Steinmetzer, Torsten
body text, p. 836 - 840 (2011/02/27)
A novel series of amidinohydrazone-derived furin inhibitors was prepared; the most potent compounds 17 and 21 inhibit furin with Ki values of 0.46 and 0.59 μM, respectively. In contrast to inhibitor 17, which still contains a guanidino residue,
Evaluation of the thiosemicarbazones of some aryl alkyl ketones and related compounds for anticonvulsant activities
Dimmock, J.R.,McColl, J.M.,Wonko, S.L.,Thayer, R.S.,Hancock, D.S.
, p. 529 - 534 (2007/10/02)
The thiosemicarbazone of acetophenone (1a) had been shown previously to afford protection against experimentally-induced seizures.This report describes the systematic chemical modification of 1a and the activities of these analogues in the maximal electro