478148-61-7

Basic information

• Product Name: Furo[2,3-c]pyridine-5-carboxaldehyde (9CI)
• Synonyms: Furo[2,3-c]pyridine-5-carboxaldehyde (9CI);Furo[2,3-c]pyridine-5-carboxaldehyde
• CAS NO: 478148-61-7
• Molecular Formula: C₈H₅NO₂
• Molecular Weight: 147.1308
• Product Categories: ALDEHYDE;PYRIDINE
• Mol File: 478148-61-7.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 261.1±20.0 °C(Predicted)
• Appearance: /
• Density: 1.322±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 2.70±0.30(Predicted)
• CAS DataBase Reference: Furo[2,3-c]pyridine-5-carboxaldehyde (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Furo[2,3-c]pyridine-5-carboxaldehyde (9CI)(478148-61-7)
• EPA Substance Registry System: Furo[2,3-c]pyridine-5-carboxaldehyde (9CI)(478148-61-7)

Safety Data

• Hazardous Substances Data: 478148-61-7(Hazardous Substances Data)

Usage

General Description

Furo[2,3-c]pyridine-5-carboxaldehyde (9CI) is a chemical compound with the molecular formula C7H5NO2. It is a heterocyclic organic compound that contains both a furo and a pyridine ring in its structure. Furo[2,3-c]pyridine-5-carboxaldehyde (9CI) is a yellow liquid at room temperature and is commonly used in the synthesis of pharmaceuticals and agrochemicals. It is also a key intermediate in the production of a variety of other organic compounds. Furo[2,3-c]pyridine-5-carboxaldehyde (9CI) is mainly used in research and industrial applications due to its versatile chemical properties and its ability to participate in various organic reactions.

Upstream product

• 478148-60-6 furo[2,3-c]pyridin-5-yl methanol 
• 79-37-8 oxalyl dichloride 
• 441044-90-2 [7-chloro-2-(trimethylsilyl)furo[2,3-c]pyridin-5-yl]methanol 
• 478148-59-3 5-hydroxymethyl-2-trimethylsilyl-furo[2,3-c]pyridine 
• 208519-38-4 2-chloro-6-(hydroxymethyl)-4-[(trimethylsilyl)ethynyl]-3-pyridinol 
• 208519-37-3 2-chloro-3-hydroxy-6-(hydroxymethyl)-4-iodopyridine 
• 208519-39-5 (7-chlorofuro[2,3-c]pyridin-5-yl)methanol 
• 208519-41-9 2-chloro-6-(hydroxymethyl)-3-pyridinol 
• 6636-78-8 2-chloro-3-hydroxypyridine 

Downstream Products

• 478148-62-8 furo[2,3-c]pyridine-5-carboxylic acid 
• 478149-53-0 PHA-543613 

Relevant articles and documents

CARBINOL DERIVATIVES HAVING HETEROCYCLIC LINKER

[Object] It is to provide a novel LXRβ agonist useful as a preventative and/or therapeutic agent for atherosclerosis; arteriosclerosis such as those resulting from diabetes; dyslipidemia; hypercholesterolemia; lipid-related diseases; inflammatory diseases that are caused by inflammatory cytokines; skin diseases such as allergic skin diseases; diabetes; or Alzheimer's disease. [Solving Means] A carbinol compound represented by the following general formula (I) or salt thereof, or their solvate: (wherein, each V and W independently show N or C—R7; each X and Y independently show CH2, C═O, SO2, etc; Z shows CH or N; each R1, R2 and R7 independently show a hydrogen atom, C1-8 alkyl group, etc.; R3 shows C1-8 alkyl group; R4 shows an optionally substituted C6-10 aryl group or an optionally substituted 5- to 11-membered heterocyclic group; R5 and R6 show a hydrogen atom, etc.; L shows a C1-8 alkyl chain optionally substituted with an oxo group, etc.; and n shows any integer of 0 to 2.)

CRYSTALLINE FUMARATE SALTS OF 1-AZABICYCLO[2.2.2]OCT SUBSTITUTED FURO[2,3-C]PYRIDINYL CARBOXAMIDE AND COMPOSITIONS AND PREPARATIONS THEREOF

The invention provides fumarate salts of N-[1-azabicyclo[2.2.2]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide, compositions, racemic mixtures, or pure enantiomers thereof, and preparation thereof. The fumarate salts are useful to treat diseases or conditions in which α7 nAChR is known to be involved. Formula (I).

Substituted 7-aza[2.2.1]bicycloheptanes for the treatment of disease

The invention provides compounds of Formula I: which may be in the form of pharmaceutical acceptable salts or compositions, are useful in treating diseases or conditions in which α7 nicotinic acetylcholine receptors (nAChRs) are known to be involved.