485841-45-0

Basic information

• Product Name: 2-Pyridinecarboxamide, 4-(4-amino-3-nitrophenoxy)-N-methyl-
• CAS NO: 485841-45-0
• Molecular Formula: C13H12N4O4
• Molecular Weight: 288.263
• Mol File: 485841-45-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-Pyridinecarboxamide, 4-(4-amino-3-nitrophenoxy)-N-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pyridinecarboxamide, 4-(4-amino-3-nitrophenoxy)-N-methyl-(485841-45-0)
• EPA Substance Registry System: 2-Pyridinecarboxamide, 4-(4-amino-3-nitrophenoxy)-N-methyl-(485841-45-0)

Safety Data

• Hazardous Substances Data: 485841-45-0(Hazardous Substances Data)

Upstream product

• 220000-87-3 4-chloro-N-methylpicolinamide 
• 610-81-1 4-hydroxy-2-nitroaniline 

Downstream Products

• 485841-46-1 4-(4-methylamino-3-nitrophenoxy)-pyridine-2-carboxylic acid methylamide 
• 611226-34-7 C₁₅H₁₁F₃N₄O₅ 
• 485841-47-2 4-(3-amino-4-methylamino-phenoxy)-pyridine-2-carboxylic acid methylamide 

Relevant articles and documents

Design and synthesis of orally bioavailable benzimidazoles as raf kinase inhibitors

A series of arylaminobenzimidazoles was designed and synthesized as Raf kinase inhibitors. Exploration of the structure-activity relationship resulted in compounds that are potent in vitro and show desirable in vivo properties.

BENZIMIDAZOLE QUINOLINONES AND USES THEREOF

Methods of inhibiting various enzymes and treating various conditions are provided that include administering to a subject a compound of Structure I or IB, a pharmaceutically acceptable salt thereof, a tautomer thereof, or a pharmaceutically acceptable salt of the tautomer. Compounds having the Structure I and IB have the following structures and have the variables described herein. Such compounds may be used to prepare medicaments for use in inhibiting various enzymes and for use in treating conditions mediated by such enzymes.