514797-97-8

Basic information

• Product Name: 2-Bromo-5-chloro-3-fluoropyridine
• Synonyms: 2-Bromo-5-chloro-3-fluoropyridine;2-Bromo-3-fluoro-5-chloropyridine
• CAS NO: 514797-97-8
• Molecular Formula: C₅H₂BrClFN
• Molecular Weight: 210.43
• Product Categories: Halides;Heterocycles
• Mol File: 514797-97-8.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 190.786 °C at 760 mmHg
• Flash Point: 69.185 °C
• Appearance: /
• Density: 1.83 g/cm³
• Vapor Pressure: 0.738mmHg at 25°C
• Refractive Index: 1.555
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 2-Bromo-5-chloro-3-fluoropyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Bromo-5-chloro-3-fluoropyridine(514797-97-8)
• EPA Substance Registry System: 2-Bromo-5-chloro-3-fluoropyridine(514797-97-8)

Safety Data

• RIDADR: UN2811
• Hazardous Substances Data: 514797-97-8(Hazardous Substances Data)

Usage

General Description

2-Bromo-5-chloro-3-fluoropyridine is a chemical compound with the molecular formula C5H2BrClFNO. It is a pyridine derivative with bromine, chlorine, and fluorine substituents. 2-Bromo-5-chloro-3-fluoropyridine is commonly used as a building block in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals. It is known for its versatile reactivity, making it an important intermediate for the production of various organic compounds. Additionally, 2-Bromo-5-chloro-3-fluoropyridine is also used as a reagent in organic synthesis and as a starting material for the development of new chemical entities. Its unique chemical properties and applications make it a valuable compound in the field of chemical research and development.

InChI:InChI=1/C5H2BrClFN/c6-5-4(8)1-3(7)2-9-5/h1-2H

Upstream product

• 514797-96-7 5-chloro-3-fluoro-2(1H)-pyridinone 
• 246847-98-3 5-chloro-3-fluoro-pyridine-2-amine 

Downstream Products

• 207994-08-9 5-chloro-3-fluoro-2-pyridinecarboxylic acid 
• 514798-01-7 2-bromo-5-chloro-3-fluoro-4-pyridinecarboxylic acid 
• 514797-99-0 3-chloro-5-fluoro-pyridine 
• 514797-98-9 5-chloro-3-fluoro-2-iodopyridine 
• 514798-07-3 3-chloro-5-fluoro-4-iodo-pyridine 
• 514798-11-9 3-chloro-5-fluoro-2-iodopyridine 
• 514798-03-9 3-chloro-5-fluoro-4-pyridinecarboxylic acid 
• 514798-20-0 methyl 3-chloro-5-fluoro-6-iodo-2-pyridinecarboxylate 
• 514798-17-5 6-bromo-3-chloro-5-fluoro-2-pyridinecarboxylic acid 
• 207994-11-4 5-chloro-3-fluoropicolinonitrile 
• 1200498-38-9 C₆H₂ClFNO₂^(1-)*Li⁽¹⁺⁾ 
• 1200498-40-3 methyl 5-chloro-3-fluoropicolinate 
• 1200498-46-9 5-cyano-3-fluoropyridine-2-carboxylic acid 

Relevant articles and documents

PYRROLOPYRIMIDINE DERIVATIVES AS NR2B NMDA RECEPTOR ANTAGONISTS

Disclosed are chemical entities of formula I: [INSERT CHEMICAL FORMULA HERE] wherein X, Y, Z, R1, R3, R4, R5 and R6 are defined herein, as NR2B subtype selective receptor antagonists. Also disclosed are pharmaceutical compositions comprising a chemical entity of formula I, and methods of treating various diseases and disorders associated with NR2B antagonism, e.g., diseases and disorders of the CNS, such as depression, by administering a chemical entity of formula I.

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