514798-03-9 Usage
Description
3-Chloro-5-fluoro-4-pyridinecarboxylic acid is an organic compound characterized by its chloro and fluoro substitutions on the pyridine ring. It serves as a key intermediate in the synthesis of various pharmaceutical compounds due to its unique structural features and reactivity.
Uses
Used in Pharmaceutical Industry:
3-Chloro-5-fluoro-4-pyridinecarboxylic acid is used as a synthetic intermediate for the preparation of Oxodihydropyridopyrimidine derivatives. These derivatives are utilized as eIF4E inhibitors, which play a crucial role in the regulation of protein synthesis and have potential applications in the treatment of various diseases, including cancer.
Check Digit Verification of cas no
The CAS Registry Mumber 514798-03-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,1,4,7,9 and 8 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 514798-03:
(8*5)+(7*1)+(6*4)+(5*7)+(4*9)+(3*8)+(2*0)+(1*3)=169
169 % 10 = 9
So 514798-03-9 is a valid CAS Registry Number.
514798-03-9Relevant articles and documents
MITOCHONDRIAL ALDEHYDE DEHYDROGENASE-2 MODULATORS AND METHODS OF USE THEREOF
-
Paragraph 00329, (2014/10/15)
The present disclosure provides compounds that function as modulators of mitochondrial aldehyde dehydrogenase-2 (ALDH2) activity, and methods of preparing these compounds.