5315-24-2Relevant articles and documents
TRICYCLIC PSYCHOPLASTOGENS AND USES THEREOF
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Paragraph 00267; 00269, (2021/12/30)
Disclosed herein are compounds, compositions, and methods for promoting neuronal growth and/or improving neuronal structure with the compounds and compositions disclosed herein. Also described are methods of treating diseases or disorders that are mediated by the loss of synaptic connectivity and/or plasticity, such as neurological diseases and disorders, with non-hallucinogenic psychoplastogens.
Pyrazolo-cyclic compound, pharmaceutical composition containing pyrazolo-cyclic compound, and preparation method and application of pyrazolo-cyclic compound
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Paragraph 0408-0412, (2021/04/26)
The invention belongs to the field of medicinal chemistry, and relates to a pyrazolo-cyclic compound, a pharmaceutical composition containing the pyrazolo-cyclic compound, and a preparation method and application of the pyrazolo-cyclic compound. Specifica
ASK1 inhibitor and application thereof
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Paragraph 0169-0173, (2020/02/10)
The invention relates to compounds represented by a general formula (I) shown in the specification, a pharmaceutically acceptable salt and ester, or a stereoisomer of the compounds. The invention alsorelates to a preparation method of the compounds, a pharmaceutical preparation and a pharmaceutical composition containing the compounds. The compounds provided by the invention can effectively inhibit the amino acid phosphorylation of ASK1 and inhibit the activation of the ASK1; therefore, the compounds can treat and/or prevent ASK1-mediated diseases and related diseases.