54606-49-4 Usage
Description
3-(AMINOMETHYL)-PROXYL, also known as 3-amino-2,2,5,5-tetramethyl-1-pyrrolidinyloxy, is a stable nitroxide radical and a useful spin label for studying biological systems. It possesses unique properties that allow it to be used in various applications, including molecular diffusion studies, radioprotection, and pharmacological research.
Uses
Used in Molecular Diffusion Studies:
3-(AMINOMETHYL)-PROXYL is used as a spin label for studying molecular diffusion in biological systems, such as its application in studying the diffusion of molecules into horse spleen ferritin. This helps researchers gain insights into the dynamics and interactions of molecules within complex biological environments.
Used as a Radioprotector:
3-(AMINOMETHYL)-PROXYL is used as an effective nonthiol radioprotector, providing protection against radiation-induced damage in various applications, such as medical and industrial settings where exposure to radiation is a concern.
Used in Pharmacological Studies:
3-(AMINOMETHYL)-PROXYL is used in pharmacological studies of myeloperoxidase-mediated hypochlorous acid production inhibition. This helps in understanding the role of this enzyme in various biological processes and its potential as a therapeutic target for certain diseases.
Used in Chemical Reactions:
3-(AMINOMETHYL)-PROXYL is involved in reduction reactions with nitroxides, which are important for the synthesis of various compounds and the study of their properties.
Used in the Synthesis of Cardioprotectants:
3-(AMINOMETHYL)-PROXYL is used as a reactant in the synthesis of adenosine methycarboxamides, which are compounds with potential cardioprotective properties. This contributes to the development of new therapeutic agents for the treatment of cardiovascular diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 54606-49-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,4,6,0 and 6 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 54606-49:
(7*5)+(6*4)+(5*6)+(4*0)+(3*6)+(2*4)+(1*9)=124
124 % 10 = 4
So 54606-49-4 is a valid CAS Registry Number.
InChI:InChI=1/C9H19N2O/c1-8(2)5-7(6-10)9(3,4)11(8)12/h7H,5-6,10H2,1-4H3
54606-49-4Relevant articles and documents
Synthesis of Isoselenocyanates
Zakrzewski, Jerzy,Huras, Bogumi?a,Kie?czewska, Anna
, p. 85 - 96 (2015/12/26)
Isoselenocyanates were synthesized by two methods under phase-transfer conditions (50% aq NaOH, CH2Cl2, Aliquat 336); the first started from isocyanides and selenium and gave isoselenocyanates in 61-89% yields, while the second started from amines and used chloroform and selenium, by applying sequentially the Hofmann isonitrile synthesis and the addition of selenium, in 4-70% yields.
Nitroxyls; VIII. Synthesis of Nitroxylphosphinimines; A Convenient Route to Amine, Isothiocyanate, Aminocarbonylaziridine, and Carbodiimide Nitroxyls
Hankovszky, H. O.,Hideg, K.,Lex, L.
, p. 147 - 149 (2007/10/02)
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