78140-52-0

Basic information

• Product Name: 3-(ISOTHIOCYANATOMETHYL)-2,2,5,5-TETRAMETHYL-1-PYRROLIDINYLOXY
• Synonyms: 3-(ISOTHIOCYANATOMETHYL)-2,2,5,5-TETRAMETHYL-1-PYRROLIDINYLOXY;3-(ISOTHIOCYANATOMETHYL)-PROXYL;3-(ISOTHIOCYANATOMETHYL)-PROXYL, FREE RADICAL;3-(ISOTHIOCYANATOMETHYL)-PROXYL, 98%, FREE RADICAL
• CAS NO: 78140-52-0
• Molecular Formula: C10H17N2OS *
• Molecular Weight: 213.32
• Product Categories: Heterocyclic Compounds;Heterocycles;Nitric Oxide Reagents;Sulfur & Selenium Compounds
• Mol File: 78140-52-0.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 322°C at 760 mmHg
• Flash Point: 113 °C
• Appearance: /
• Density: 1.1186 (rough estimate)
• Vapor Pressure: 5.93E-05mmHg at 25°C
• Refractive Index: 1.5650 (estimate)
• Storage Temp.: 0-6°C
• CAS DataBase Reference: 3-(ISOTHIOCYANATOMETHYL)-2,2,5,5-TETRAMETHYL-1-PYRROLIDINYLOXY(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(ISOTHIOCYANATOMETHYL)-2,2,5,5-TETRAMETHYL-1-PYRROLIDINYLOXY(78140-52-0)
• EPA Substance Registry System: 3-(ISOTHIOCYANATOMETHYL)-2,2,5,5-TETRAMETHYL-1-PYRROLIDINYLOXY(78140-52-0)

Safety Data

• Hazard Codes: Xn
• Statements: 20/21/22-36/37/38
• Safety Statements: 24/25-36-26
• Hazardous Substances Data: 78140-52-0(Hazardous Substances Data)

Usage

Chemical Properties

YELLOW CRYSTALLINE POWDER

Uses

3-(Isothiocyanatomethyl)-2,2,5,5-tetramethyl-1-pyrrolidinyloxy (cas# 78140-52-0) is a compound useful in organic synthesis.

InChI:InChI=1/C10H18N2OS/c1-9(2)5-8(6-11-7-14)10(3,4)12(9)13/h8,13H,5-6H2,1-4H3/t8-/m1/s1

Upstream product

• 75-15-0 carbon disulfide 
• 78140-46-2 C₂₇H₃₂N₂OP 
• 463-71-8 thiophosgene 
• 54606-49-4 3-Methylamino-2,2,5,5-tetramethyl-1-pyrrolidinyloxy 
• 45985-26-0 4-oxo-2,2,6,6-tetramethylpiperidin-oxyl 
• 46147-12-0 3-carbamoyl-2,2,5,5-tetramethylpyrrolidin-1-yloxy 
• 27298-75-5 3-(hydroxymethyl)-2,2,5,5-tetramethylpyrrolidinyl-1-oxy 
• 78151-25-4 3-azidomethyl-2,2,5,5-tetramethyl-2,3,4,5-tetrahydropyrrole-1-oxyl 
• 78151-24-3 2,2,5,5-tetramethyl-3-p-toluenesulfonyloxy-2,3,4,5-tetrahydropyrrole-1-oxyl 

Relevant articles and documents

Reaction of Nitroxides with Sulfur Containing Compounds II [1]. Preparation of Nitroxides Bearing an Isothiocyanate Substituent in View of the Nitroxyl Group Reduction with Thiophosgene

The reaction of thiophosgene with 2,2,6,6-tetramethylpiperidine-1-oxyl (used as a model nitroxyl radical) was examined. 2,2,6,6-Tetramethylpiperidine and 2,2,6,6-tetramethyl-1-hydroxypiperidine were identified as products. The reaction is not competitive with the reaction of thiophosgene with an amino group. Thus, three nitroxides with an isothiocyanate group were synthesized from thiophosgene and the nitroxides containing the amino substituent.