73792-22-0 Usage
Description
1-(4-amino-3-fluorophenyl)ethan-1-one is an organic compound characterized by its unique molecular structure featuring a fluorine atom at the 3rd position and an amino group at the 4th position on a phenyl ring, attached to an ethanone group. 1-(4-amino-3-fluorophenyl)ethan-1-one is known for its potential applications in various chemical and pharmaceutical processes due to its reactive functional groups.
Uses
Used in Pharmaceutical Industry:
1-(4-amino-3-fluorophenyl)ethan-1-one is used as a starting material for the synthesis of various pharmaceutical compounds. Its unique structure allows for the creation of a wide range of derivatives with potential therapeutic applications.
Used in Chemical Synthesis:
1-(4-amino-3-fluorophenyl)ethan-1-one serves as a key intermediate in the preparation of complex organic molecules, particularly in the synthesis of 2-Amino-5-[(cyclopentylamino)acetyl]-3-fluoro-benzonitrile. 1-(4-amino-3-fluorophenyl)ethan-1-one is an example of how 1-(4-amino-3-fluorophenyl)ethan-1-one can be utilized to produce molecules with specific properties and potential applications in various fields.
Check Digit Verification of cas no
The CAS Registry Mumber 73792-22-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,3,7,9 and 2 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 73792-22:
(7*7)+(6*3)+(5*7)+(4*9)+(3*2)+(2*2)+(1*2)=150
150 % 10 = 0
So 73792-22-0 is a valid CAS Registry Number.
InChI:InChI=1/C8H8FNO/c1-5(11)6-2-3-8(10)7(9)4-6/h2-4H,10H2,1H3
73792-22-0Relevant articles and documents
Silver-catalyzed intermolecular amination of fluoroarenes
Wang, Yu,Wei, Chenlong,Tang, Ruyun,Zhan, Haosheng,Lin, Jing,Liu, Zhenhua,Tao, Weihua,Fang, Zhongxue
supporting information, p. 6191 - 6194 (2018/09/10)
A novel highly selective Ag-catalyzed intermolecular amination of fluoroarenes has been developed. This transformation starts from readily available 4-carbonyl fluorobenzene and NaN3 or other nitrogen-source, via amination followed by C-F bond cleavage, thus affording the desired 4-carbonyl arylamine products under mild conditions. The reaction is accelerated using a small amount of water. This pathway is distinct from a previously reported radical amination reaction.
NOVEL COMPOUNDS, ISOMER THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONIST; AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME
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Page/Page column 44; 83-84, (2008/06/13)
This present invention relates to novel compounds, isomer thereof or pharmaceutically acceptable salts thereof as vanilloid receptor (Vanilloid Receotor 1; VR1; TRPV1 )antagonist; and a pharmaceutical composition containing the same. The present invention provides a pharmaceutical composition for preventing or treating a disease such as pain, migraine, arthralgia, neuralgia, neuropathies, nerve injury, skin disorder, urinary bladder hypersensitiveness, irritable bowel syndrome, fecal urgency, a respiratory disorder, irritation of skin, eye or mucous membrane, stomach-duodenal ulcer, inflammatory diseases, ear disease, and heart disease.