743438-34-8

Basic information

• Product Name: (3ALPHAR,6ALPHAS)-TETRAHYDRO-1H-CYCLOPENTA[C]FURAN-1,3(3AH)-DIONE (3)
• Synonyms: (3ALPHAR,6ALPHAS)-TETRAHYDRO-1H-CYCLOPENTA[C]FURAN-1,3(3AH)-DIONE (3)
• CAS NO: 743438-34-8
• Molecular Formula: C₇H₈O₃
• Molecular Weight: 0
• Mol File: 743438-34-8.mol
• Article Data: 11

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (3ALPHAR,6ALPHAS)-TETRAHYDRO-1H-CYCLOPENTA[C]FURAN-1,3(3AH)-DIONE (3)(CAS DataBase Reference)
• NIST Chemistry Reference: (3ALPHAR,6ALPHAS)-TETRAHYDRO-1H-CYCLOPENTA[C]FURAN-1,3(3AH)-DIONE (3)(743438-34-8)
• EPA Substance Registry System: (3ALPHAR,6ALPHAS)-TETRAHYDRO-1H-CYCLOPENTA[C]FURAN-1,3(3AH)-DIONE (3)(743438-34-8)

Safety Data

• Hazardous Substances Data: 743438-34-8(Hazardous Substances Data)

Usage

General Description

(3α,6α)-Tetrahydro-1H-cyclopenta[c]furan-1,3(3αH)-dione (3) is an organic chemical compound with a molecular formula C6H8O3. It is a cyclic diketone that belongs to the furanone class of compounds. This chemical is also known as 3-deoxy-3-acetyl-alpha-l-rhamnofuranose and is commonly used in synthetic organic chemistry as a building block for the preparation of various pharmaceuticals and natural products. Its unique cyclic structure and functional groups make it an important intermediate in the synthesis of bioactive molecules and pharmaceutical ingredients.

Upstream product

• 50483-99-3 trans-DL-1,2-cyclopentanedicarboxylic acid 
• 1461-96-7 cis-1,2-cyclopentanedicarboxylic acid 
• 80656-14-0 trans-1,2-cyclopentanedicarboxylic acid 
• 90474-13-8 diethyl cyclopentane-1,2-dicarboxylate 
• 30132-23-1 ethyl 3-bromo-2-oxocyclohexanecarboxylate 
• 1655-07-8 ethyl 2-oxocyclohexane carboxylate 
• 118577-36-9 ethyl 5-bromo-2-oxocyclohexanecarboxylate 
• 21917-20-4 (trans)-1,2-cyclopentanedicarboxylic acid 

Downstream Products

• 4841-91-2 dimethyl cis-1,2-cyclopentanedicarboxylate 
• 75658-83-2 cis-1,2-bis(hydroxymethyl)cyclopentane 
• 1461-96-7 cis-1,2-cyclopentanedicarboxylic acid 
• 151710-39-3 N-(4-methoxyphenyl)-cis-cyclopentane-1,2-dicarboximide 
• 111939-08-3 N-benzyl-3-azabicyclo[3.3.0]octane-2,4-dione 
• 88315-64-4 (1S,2R)-cis-2-methoxycarbonyl-cyclopentane-1-carboxylic acid 
• 88335-90-4 (1R,2S)-cis-2-methoxycarbonyl-cyclopentane-1-carboxylic acid 
• 40482-10-8 2-carbamoylcyclopentanecarboxylic acid 
• 198022-67-2 (1R,2S)-Cyclopentane-1,2-dicarboxylic acid mono-((E)-3-phenyl-allyl) ester 
• 648433-16-3 (1S,2R)-cis-2-benzyloxycarbonyl-cyclopentane-1-carboxylic acid 
• 501666-10-0 (1S,2S)-Cyclopentane-1,2-dicarbonyl dichloride 
• 889888-79-3 (1R,2R)-2-[2'-hydroxy-1'-(R)-phenylethylcarbamoyl]-cyclopentane-1-carboxylic acid 
• 889888-78-2 (1R,2R)-2-[2'-hydroxy-1'-(R)-phenylethylcarbamoyl]-cyclopentane-1-carboxylic acid methyl ester 

Relevant articles and documents

NOVEL HEPATITIS C VIRUS INHIBITORS

The invention provides compounds of formula (I): wherein Rings A and A' are independently 5-membered optionally substituted aromatic heterocycles; Q is C(=O)NR1R1' or formula U is C(R4)2, O, S, S(=O)2, C(R4)2C(R4)2, CH2O, OCH2, CH2S, SCH2, CH2S(=O)2, S(=O)CH2 or C=C(Ru )2; X is CH2, CHR12, CR12R12, O, S, S(=O)2 or NRx; m is 0, 1, 2 or 3; n is 0, 1, 2 or 3; the other variables are as defined in the claims, which are of use in the treatment or prophylaxis of hepatitis C virus infection, and related aspects.

Ruthenium(salen)-catalyzed aerobic oxidative desymmetrizatin of meso-diols and its kinetics

Chiral (nitrosyl)ruthenium(salen) complexes were found to be efficient catalysts for aerobic oxidative desymmetrization of meso-diols under photoirradiation to give optically active tactols. The scope of the applicability of this reaction ranges widely from acyclic diols to mono-cyclic diols, although fine ligand-tuning of the ruthenium(salen) complexes was required to attain high enantioselectivity (up to 93% ee). In particular, the nature of the apical ligand was found to affect not only enantioselectivity but also kinetics of the desymmetrization reaction. Spectroscopic analysis of the oxidation disclosed that irradiation of visible light is indispensable not only for dissociation of the nitrosyl ligand but also for single electron transfer from the alcohol-bound ruthenium ion to dioxygen.

Synthesis of cyclooctenones using intramolecular hydroacylation

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