75081-40-2Relevant articles and documents
Selective hydrogenation of benzoic acid to cyclohexane carboxylic acid over microwave-activated Ni/carbon catalysts
Lu,Shen,He,Jing,Tao,Hu,Nie,Zhou,Xia
, p. 53 - 61 (2017/12/06)
High yields of cyclohexane carboxylic acids were obtained by direct hydrogenation of aromatic carboxylic acids over different Ni/carbon catalysts having distinctive surface properties. The catalysts were characterized by SEM, TEM, H2-TPR and N2 adsorption isotherms for the determination of BET surface area and porosity. The hydrogenation reaction was carried out in batch pressure reactor in gas-liquid phase at 200 °C. High selectivity (100%) of cyclohexane carboxylic acids at 86.2 mol% conversion of benzoic acid was achieved over microwave-activated biochar supported non-precious metal Ni catalyst. The 10%Ni/CSC-b catalyst has been investigated for hydrogenation of benzoic acid to cyclohexane carboxylic acids and shown little deactivation in stability test. The effects of Ni loading, high dispersion of Ni species, appropriate power of microwave heating and strong interaction of Ni species with carbon are of benefit to the reaction.
Isothiourea-mediated asymmetric O- to C-carboxyl transfer of oxazolyl carbonates: Structure-selectivity profiles and mechanistic studies
Joannesse, Caroline,Johnston, Craig P.,Morrill, Louis C.,Woods, Philip A.,Kieffer, Madeleine,Nigst, Tobias A.,Mayr, Herbert,Lebl, Tomas,Philp, Douglas,Bragg, Ryan A.,Smith, Andrew D.
, p. 2398 - 2408 (2012/03/27)
The structural motif within a series of tetrahydropyrimidine-based isothioureas necessary for generating high asymmetric induction in the asymmetric Steglich rearrangement of oxazolyl carbonates is fully explored, with crossover and dynamic 19F NMR experiments used to develop a mechanistic understanding of this transformation. Copyright
Synthesis and characterisation of helical β-peptide architectures that contain (S)-β3-HDOPA(crown ether) derivatives
Dutot, Laurence,Gaucher, Anne,Elkassimi, Khadidja,Drapeau, Jeremy,Wakselman, Michel,Mazaleyrat, Jean-Paul,Peggion, Cristina,Formaggio, Fernando,Toniolo, Claudio
supporting information; scheme or table, p. 3154 - 3163 (2009/04/11)
A new set of β-amino acids that carry various crown ether receptors on their side chains of the general formula (S)-β3-HDOPA(crown ether) (HDOPA: homo-3,4-dihydroxyphenylalanine; (crown ether): [15]crown-5 ([15-C-5]), [18]crown-6 ([18-C-6]), [21]crown-7 ([21-C-7]), 1,2-Benzo-[24]crown- 8 ([Benzo-24-C-8]) and (R)-Binol-[20]crown-6 ([(R)-Binol-20-C-6])) was prepared. Peptides that are based on these new crowned β-amino acids combined with (1S,2S)-ACHC (2-aminocyclohexanecarboxylic acid), which is known to be a potent 314-helix inducer, to the hexamer level, with two crowned residues at the i and i+3 posi_tions of the main-chain, were synthesized in solution by stepwise coupling using Boc-Na-protection (Boc: tert-butoxycarbonyl) and the EDC/HOAt Cactivation method. Their conformational analysis was performed by using FTIR absorption, NMR and CD spectroscopy techniques. Our results are in full agreement with a 314-helix conformation.