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82543-15-5

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  • (3b,5b,15a,16a)-15,16-Dihydro-3,5-dihydroxy-3'H-cycloprop[15,16]androsta-6,15-dien-17-one Manufacturer/High quality/Best price/In stock

    Cas No: 82543-15-5

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  • (3b,5b,15a,16a)-15,16-Dihydro-3,5-dihydroxy-3'H-cycloprop[15,16]androsta-6,15-dien-17-one Manufacturer/High quality/Best price/In stock CAS NO.82543-15-5

    Cas No: 82543-15-5

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  • (3β,5β,15α,16α)-15,16-Dihydro-3,5-dihydroxy-3'H-cycloprop[15,16]androsta-6,15-dien-17-one

    Cas No: 82543-15-5

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82543-15-5 Usage

Description

(3b,5b,15a,16a)-15,16-Dihydro-3,5-dihydroxy-3'H-cycloprop[15,16]androsta-6,15-dien-17-one is a white solid impurity of the synthetic progestogen Drospirenone (D453200). It is characterized by its unique cyclopropane ring fused to the androstane steroid nucleus and possesses two hydroxyl groups at the 3 and 5 positions.

Uses

Used in Pharmaceutical Industry:
(3b,5b,15a,16a)-15,16-Dihydro-3,5-dihydroxy-3'H-cycloprop[15,16]androsta-6,15-dien-17-one is used as an intermediate in the preparation of aldosterone antagonists. These antagonists are important for the treatment of various conditions, including hypertension, heart failure, and primary aldosteronism, by blocking the effects of aldosterone, a hormone that regulates blood pressure and electrolyte balance.
Additionally, due to its structural similarity to Drospirenone, it may have potential applications in the development of new progestogens or other steroidal drugs with improved pharmacological properties and reduced side effects. Further research and development are required to explore its full potential in the pharmaceutical field.

Check Digit Verification of cas no

The CAS Registry Mumber 82543-15-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,2,5,4 and 3 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 82543-15:
(7*8)+(6*2)+(5*5)+(4*4)+(3*3)+(2*1)+(1*5)=125
125 % 10 = 5
So 82543-15-5 is a valid CAS Registry Number.

82543-15-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 3β,5β-Dihydroxy-15β,16β-methylene-androst-6-en-17-one

1.2 Other means of identification

Product number -
Other names 3β,5-dihydroxy-15β,16β-methylene-5β-androst-6-en-17-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:82543-15-5 SDS

82543-15-5Relevant articles and documents

Synthese von Spirorenon, einem neuen stark wirksamen Aldosteron-Antagonisten

Bittler, Dieter,Hofmeister, Helmut,Laurent, Henry,Nickisch, Klaus,Petzoldt, Karl,et al.

, p. 718 - 719 (2007/10/02)

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