82543-16-6 Usage
Description
3b,5-Dihydroxy-6b,7b:15b,16b-dimethylene-5b-androstan-17-one is a white solid compound that serves as an intermediate in the synthesis of Drospirenone, a progestin hormone used in contraceptives and hormone replacement therapy.
Used in Pharmaceutical Industry:
3b,5-Dihydroxy-6b,7b:15b,16b-dimethylene-5b-androstan-17-one is used as an intermediate in the synthesis of Drospirenone for its role in contraceptives and hormone replacement therapy. Its chemical properties make it a suitable precursor for the production of this hormone.
Check Digit Verification of cas no
The CAS Registry Mumber 82543-16-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,2,5,4 and 3 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 82543-16:
(7*8)+(6*2)+(5*5)+(4*4)+(3*3)+(2*1)+(1*6)=126
126 % 10 = 6
So 82543-16-6 is a valid CAS Registry Number.
InChI:InChI=1/C21H32O3/c1-19-8-7-16-15(17(19)13-3-4-14(13)18(19)23)6-10-21(24)11-12(22)5-9-20(16,21)2/h12-17,22,24H,3-11H2,1-2H3/t12-,13+,14-,15+,16-,17-,19-,20+,21-/m0/s1
82543-16-6Relevant articles and documents
Process for the preparation of Drospirenone
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Page/Page column 11, (2009/02/10)
A process for the preparation of Drospirenone (I) according to the following scheme wherein the substituent R is defined in the description. The process improves the product yield and purity by reducing the formation of undesired side-products and is particularly convenient for industrial-scale manufacturing.
A process for the preparation of drospirenone
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Page/Page column 4; 9; 14, (2010/02/13)
A process is described for preparing drospirenone, a synthetic steroid with progestogenic, antimineralocorticoid and antiandrogenic activity, useful for the preparation of pharmaceutical compositions with contraceptive action, starting from 5,6β-epoxy-7β-hydroxy-15β,16β-methylene-3β-pivaloyloxy-5β-androstan-17-one.
