83408-88-2

Basic information

• Product Name: 2-(1H-Benzimidazol-2-ylthio)-N-(2-methoxyphenyl)acetamide
• Synonyms: 2-(1H-Benzimidazol-2-ylthio)-N-(2-methoxyphenyl)acetamide
• CAS NO: 83408-88-2
• Molecular Formula: C₁₆H₁₅N₃O₂S
• Molecular Weight: 313.3742
• Mol File: 83408-88-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.36g/cm³
• Refractive Index: 1.692
• CAS DataBase Reference: 2-(1H-Benzimidazol-2-ylthio)-N-(2-methoxyphenyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(1H-Benzimidazol-2-ylthio)-N-(2-methoxyphenyl)acetamide(83408-88-2)
• EPA Substance Registry System: 2-(1H-Benzimidazol-2-ylthio)-N-(2-methoxyphenyl)acetamide(83408-88-2)

Safety Data

• Hazardous Substances Data: 83408-88-2(Hazardous Substances Data)

Usage

Chemical class

Acetamides

Benzimidazole derivative

Thioether derivative

Potential pharmaceutical applications

Antifungal, antitumor, and antiviral activities

Unique structural feature

Presence of the thioether group in the benzimidazole ring

Need for further research

To fully understand its pharmacological properties and potential uses

InChI:InChI=1/C16H15N3O2S/c1-21-14-9-5-4-8-13(14)17-15(20)10-22-16-18-11-6-2-3-7-12(11)19-16/h2-9H,10H2,1H3,(H,17,20)(H,18,19)

Upstream product

• 55860-22-5 2-chloro-N-(2-methoxyphenyl)acetamide 
• 134469-07-1 Benzimidazol-2-thiol 
• 32428-69-6 2-bromo-N-(2-methoxy-phenyl)-acetamide 
• 3042-01-1 thiazolo[3,2-a]benzimidazol-3(2H)-one 
• 90-04-0 2-methoxy-phenylamine 

Relevant articles and documents

Spectroscopic behavior, FMO, NLO and substitution effect of 2-(1H-Benzo[d]imidazole-2-ylthio)-N-o-substituted-acetamides: Experimental and theoretical approach

The benzimidazole-based derivatives 2a-c were designed and synthesized via C–N coupling reaction and experimentally characterized by infrared spectroscopy (FT-IR), nuclear magnetic resonance (1H NMR) spectroscopy and mass spectrometry (MS). The

Synthesis and CNS Activity of 2-(N-Arylaminoacetylmercapto)- and 2-(N-Arylacetamidomercapto)-benzimidazoles

The title mercaptobenzimidazoles (1a-t) have been synthesised and screened for their anticonvulsant and monoamine oxidase (MAO) inhibitory activities.Some of the compounds provide 80percent protection against pentylenetetrazole-induced convulsions and max