941293-00-1

Basic information

• Product Name: 3-(4-tert-butoxyphenyl)propionaldehyde
• Synonyms: 3-(4-tert-butoxyphenyl)propionaldehyde
• CAS NO: 941293-00-1
• Molecular Weight: 206.285
• Mol File: 941293-00-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 3-(4-tert-butoxyphenyl)propionaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-tert-butoxyphenyl)propionaldehyde(941293-00-1)
• EPA Substance Registry System: 3-(4-tert-butoxyphenyl)propionaldehyde(941293-00-1)

Safety Data

• Hazardous Substances Data: 941293-00-1(Hazardous Substances Data)

Upstream product

• 132307-87-0 3-(4-tert-butoxyphenyl)-propan-1-ol 
• 106-44-5 p-cresol 
• 15359-98-5 4-(tert-butoxy)toluene 
• 1400684-94-7 3-(4-(tert-butoxy)phenyl)-N-methoxy-N-methylpropanamide 
• 57699-45-3 p-tert-butoxybenzaldehyde 
• 21323-98-8 3-(4-tert-butoxyphenyl)-propionic acid 
• 155904-35-1 3-(4-tert-butoxy-phenyl)-acrylic acid 
• 5597-50-2 3-(4-hydroxyphenyl)propionic acid methyl ester 

Downstream Products

• 941293-02-3 (S)-β-4-tert-butoxyphenyl-γ-(S)-N-benzyl-α-methylbenzylamino-propylalcohol 
• 941293-01-2 C₁₄H₂₃NO₂ 
• 941293-03-4 (s)-β-4-tert-butoxylphenyl-γ-Fmoc-amino-propylalcohol 

Relevant articles and documents

Enolesters as chain end-functionalizing agents for the living ring opening metathesis polymerization

Functional enolethers have previously been used to introduce functional end groups at the chain end of ruthenium carbene complex initiated living ring opening metathesis polymers. Here, we investigated whether the weaker π-donating enolesters could equally be used in regio selective reactions with ruthenium carbene complexes and thus as polymer end-functionalization reagents. Enolesters such as vinyl acetate, butenyl acetate, 3-(4-(tert-butoxy)phenyl)propenyl acetate and 6-(((benzyloxy)carbonyl)amino)hex-1-en-1-yl acetate were used as living ROMP terminating agents. All gave the expected end groups proving that enolesters are synthetically easily accessible targets for living ROMP end-functionalization.

CONCISE BETA2-AMINO ACID SYNTHESIS VIA ORGANOCATALYTIC AMINOMETHYLATION

The present invention provides a method for the synthesis of ?2-amino acids. The method also provides methods yielding a-substituted ?-amino aldehydes and ?-substituted γ-amino alcohols. The present method according to this invention allows for increased yield and easier purification using minimal chromatography or crystallization. The methods described herein are based on an aldehyde aminomethylation which involves a Mannich reaction between an aldehyde and a formaldehyde-derived N,O-acetal (iminium precursor) and a catalyst, such as, for example, L-proline or a pyrrolidine. The invention allows for large scale, commercial preparation of ?2-amino acids.