(R)-(+)-1-AMINO-2-(METHOXYMETHYL)PYRROLIDINE

The systematic name of (R)-(+)-1-Amino-2-(methoxymethyl)pyrrolidine is (2R)-2-(methoxymethyl)pyrrolidin-1-amine. With the CAS registry number 72748-99-3, it is also named as 1-pyrrolidinamine, 2-(methoxymethyl)-, (2R)-. The product's categories are Pyrrolidine; Chiral; Asymmetric Synthesis; Synthetic Organic Chemistry; Chiral Compound. It is colorless to light yellow liquid which should be sealed in the container and stored in the cool and dry place.

The other characteristics of this product can be summarized as: (1)ACD/LogP: -1.25; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -3.62; (4)ACD/LogD (pH 7.4): -1.91; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 1; (8)ACD/KOC (pH 7.4): 1.07; (9)#H bond acceptors: 3; (10)#H bond donors: 2; (11)#Freely Rotating Bonds: 3; (12)Polar Surface Area: 15.71 Å²; (13)Index of Refraction: 1.47; (14)Molar Refractivity: 36.63 cm³; (15)Molar Volume: 131.2 cm³; (16)Polarizability: 14.52×10^-24 cm³; (17)Surface Tension: 33.1 dyne/cm; (18)Density: 0.991 g/cm³; (19)Flash Point: 64.9 °C; (20)Enthalpy of Vaporization: 41.99 kJ/mol; (21)Boiling Point: 183.7 °C at 760 mmHg; (22)Vapour Pressure: 0.761 mmHg at 25°C.

Uses of (R)-(+)-1-Amino-2-(methoxymethyl)pyrrolidine: It can react with 2-oxo-cyclohexanecarbonitrile to get (2R)-1-((2R/S)-2-cyanocyclohexylideneamino)-2-methoxymethylpyrrolidine. This reaction needs reagent p-TsOH and solvent cyclohexane by heating. The reaction time is 12 hours. The yield is 72%.

When you are using this chemical, please be cautious about it as the following:
It is irritating to eyes, respiratory system and skin. So people should avoid contact with skin and eyes. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. If you want to contact this product, you must wear suitable protective clothing.

People can use the following data to convert to the molecule structure.
1. SMILES:O(C)C[C@@H]1N(N)CCC1
2. InChI:InChI=1/C6H14N2O/c1-9-5-6-3-2-4-8(6)7/h6H,2-5,7H2,1H3/t6-/m1/s1 
3. InChIKey:BWSIKGOGLDNQBZ-ZCFIWIBFBA