1-Bromo-3-methoxypropane supplier

Name
1-Bromo-3-methoxypropane
EINECS
CAS No. 36865-41-5
Article Data15
CAS DataBase
Density 1.341 g/cm³
Solubility
Melting Point
Formula C₄H₉BrO
Boiling Point 103.5 °C at 760 mmHg
Molecular Weight 153.019
Flash Point 30.6 °C
Transport Information
Appearance
Safety 26-36/37/39
Risk Codes 36/37/38
Molecular Structure
Hazard Symbols Xi
Synonyms Ether,3-bromopropyl methyl (7CI);3-Bromopropyl methyl ether;propane, 1-bromo-3-methoxy-;
PSA 9.23000
LogP 1.41780

Synthetic route

: 420-37-1
trimethoxonium tetrafluoroborate

: 627-18-9
1-bromo-3-propanol

: 36865-41-5
3-bromopropanol methyl ether

Conditions

Conditions	Yield
In dichloromethane 1.) reflux, 2.) K2CO3, water;	58%

: 1589-49-7
methoxypropanol

: 36865-41-5
3-bromopropanol methyl ether

Conditions

Conditions	Yield
With N-Bromosuccinimide; triphenylphosphine at 25℃; for 16h;	51%
With bromine; triphenylphosphine In pyridine; dichloromethane for 2h;	50%
With phosphorus tribromide for 2h; Ambient temperature;	40%

: 186581-53-3, 908094-01-9
diazomethane

: 627-18-9
1-bromo-3-propanol

: 36865-41-5
3-bromopropanol methyl ether

Conditions

Conditions	Yield
With boron trifluoride diethyl etherate In diethyl ether at -10℃;	22%
With H(+)-zeolite-X In benzene at 25℃; for 0.5h;	89 % Chromat.

: 67-56-1
methanol

: 109-64-8
1,3-dibromo-propane

: 36865-41-5
3-bromopropanol methyl ether

Conditions

Conditions	Yield
With zinc(II) oxide at 100℃;

: 124-41-4
sodium methylate

: 109-64-8
1,3-dibromo-propane

: 36865-41-5
3-bromopropanol methyl ether

Conditions

Conditions	Yield
With methanol
With methanol

: 6-bromo-2-(3,4-difluorophenyl)-4H-benzo[1,4]oxazin-3-one

: 36865-41-5
3-bromopropanol methyl ether

: 949008-25-7
C18H16BrF2NO3

Conditions

Conditions	Yield
With potassium carbonate In acetonitrile for 16h; Heating;	100%

: 6-bromo-2-(4-fluorophenyl)-4H-benzo[1,4]oxazin-3-one

: 36865-41-5
3-bromopropanol methyl ether

: C18H17BrFNO3

Conditions

Conditions	Yield
With potassium carbonate In acetonitrile for 14h; Heating;	100%

: 36865-41-5
3-bromopropanol methyl ether

: 64297-55-8
3-methoxy-1-propanesulfonyl chloride

Conditions

Conditions	Yield
Stage #1: 3-bromopropanol methyl ether With sodium sulfite In water for 24h; Heating / reflux; Stage #2: With trichlorophosphate at 80 - 100℃; for 7h;	100%

: 36865-41-5
3-bromopropanol methyl ether

: 554-84-7
meta-nitrophenol

: 1041399-44-3
1-(3-methoxypropoxy)-3-nitrobenzene

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 90℃;	100%
Stage #1: meta-nitrophenol With sodium hydride In N,N-dimethyl-formamide for 0.166667h; Stage #2: 3-bromopropanol methyl ether In N,N-dimethyl-formamide at 20℃; for 18.0833h;	83%

: 621-59-0
isovanillin

: 36865-41-5
3-bromopropanol methyl ether

: 172900-75-3
4-methoxy-3-(3-methoxypropoxy)benzaldehyde

Conditions

Conditions	Yield
With potassium carbonate In acetonitrile for 3h; Reflux;	100%
With N-benzyl-N,N,N-triethylammonium chloride; potassium carbonate In acetonitrile Reflux;	100%
With potassium carbonate In acetonitrile	95%

: 36865-41-5
3-bromopropanol methyl ether

: 1392314-22-5
N-(2-(1,1-dioxido-4-thiomorpholinyl)ethyl)-2-nitrobenzenesulfonamide

: 1392314-27-0
N-(2-(1,1-dioxido-4-thiomorpholinyl)ethyl)-N-(3-methoxypropyl)-2-nitrobenzenesulfonamide

Conditions

Conditions	Yield
Stage #1: N-(2-(1,1-dioxido-4-thiomorpholinyl)ethyl)-2-nitrobenzenesulfonamide With caesium carbonate In N,N-dimethyl-formamide at 20℃; for 0.5h; Stage #2: 3-bromopropanol methyl ether With caesium carbonate In N,N-dimethyl-formamide at 20 - 70℃; for 73h;	100%

: 36865-41-5
3-bromopropanol methyl ether

: 1428130-30-6
methyl 1-(5-chloro-2-hydroxybenzyl)-1H-indole-4-carboxylate

: C21H22ClNO4

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 60℃;	100%

: 36865-41-5
3-bromopropanol methyl ether

: ethyl 9'-hydroxy-10'-methoxy-2'-oxo-2',7'-dihydrospiro[cyclopentane-1,6'-pyrido[2,1-a]isoquinoline]-3'-carboxylate

: ethyl 10'-methoxy-9'-(3-methoxypropoxy)-2'-oxo-2',7'-dihydrospiro[cyclopentane-1,6'-pyrido[2,1-a]isoquinoline]-3'-carboxylate

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 20℃;	100%

: 36865-41-5
3-bromopropanol methyl ether

: (S)-tert-butyl (1-(6-chloro-5-hydroxy-2-iodopyridin-3-yl)-3,3-dimethylbutan-2-yl)carbamate

: tert-butyl (S)-(1-(6-chloro-2-iodo-5-(3-methoxypropoxy)pyridin-3-yl)-3,3-dimethylbutan-2-yl)carbamate

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 80℃; for 3h;	100%

: 36865-41-5
3-bromopropanol methyl ether

: 858855-11-5
5-bromo-2-iodo-phenol

: 4-bromo-1-iodo-2-(3-methoxypropoxy)benzene

Conditions

Conditions	Yield
With potassium carbonate In water; ethyl acetate; N,N-dimethyl-formamide	99.9%

: 36865-41-5
3-bromopropanol methyl ether

: 183802-98-4
5-bromo-2-chlorophenol

: 897954-59-5
4-bromo-1-chloro-2-(3-methoxypropoxy)benzene

Conditions

Conditions	Yield
With potassium carbonate In acetone at 50℃; for 15h; Solvent;	99.44%
With potassium carbonate In N,N-dimethyl-formamide at 50℃; for 16h;	91%
With potassium carbonate at 20℃; for 16h;	89.1%

: 36865-41-5
3-bromopropanol methyl ether

: 22717-56-2
4-bromo-2-Hydroxybenzoic Acid Methylester

: 1399849-96-7
methyl 4-bromo-2-(3-methoxypropoxy)benzoate

Conditions

Conditions	Yield
With potassium carbonate In acetonitrile at 80℃; for 12h; Temperature;	99.3%
With potassium carbonate In acetonitrile at 80℃; for 12h;	99.3%

: 36865-41-5
3-bromopropanol methyl ether

: 37942-01-1
5-bromo-2-methoxyphenol

: 173336-76-0
4-bromo-1-methoxy-2-(3-methoxypropoxy)benzene

Conditions

Conditions	Yield
With potassium carbonate; potassium iodide In acetonitrile for 24h; Reflux;	99%
With potassium carbonate In N,N-dimethyl-formamide at 25℃; for 8h;	99.12%
With potassium carbonate In N,N-dimethyl-formamide	99%

: 1003-29-8
2-pyrrole aldehyde

: 36865-41-5
3-bromopropanol methyl ether

: 869106-75-2
1-(3-methoxypropyl)-1H-pyrrole-2-carbaldehyde

Conditions

Conditions	Yield
With sodium hydride In N,N-dimethyl-formamide at 20℃; for 16h;	99%
With sodium hydride In tetrahydrofuran for 4.25h; Inert atmosphere;	60%

: 1126-09-6
4-carbethoxypiperidine

: 36865-41-5
3-bromopropanol methyl ether

: 1249604-45-2
ethyl 1-(3-methoxy-propyl)-piperidin-4-carboxylate

Conditions

Conditions	Yield
With caesium carbonate In acetonitrile for 4h; Reflux;	99%
With caesium carbonate In acetonitrile for 4h; Reflux;	99%
With potassium carbonate In acetonitrile at 25 - 85℃; for 7.5h; Inert atmosphere; Reflux; Large scale;	98.8%
With potassium carbonate In acetonitrile for 7.25h; Reflux;	90%

: 36865-41-5
3-bromopropanol methyl ether

: 30186-18-6
4'-bromo-2'-hydroxyacetophenone

: 905831-23-4
1-(4-bromo-2-(3-methoxypropoxy)phenyl)ethanone

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 20℃;	99%

: 36865-41-5
3-bromopropanol methyl ether

: 27684-84-0
5-bromo-2-nitrophenol

: 4-bromo-2-(3-methoxypropoxy)-1-nitrobenzene

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 50℃;	99%

: 36865-41-5
3-bromopropanol methyl ether

: 143360-01-4
N-(4-bromo-2-methoxyphenyl)acetamide

: N-(4-bromo-2-methoxyphenyl)-N-(3-methoxypropyl)acetamide

Conditions

Conditions	Yield
With sodium hydride In N,N-dimethyl-formamide; mineral oil at 20℃; for 12h;	99%

: 36865-41-5
3-bromopropanol methyl ether

: 153241-03-3
2-(benzyloxy)-5-bromophenol

: 1-(benzyloxy)-4-bromo-2-(3-methoxypropoxy)benzene

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 50℃;	98.1%
With potassium carbonate In N,N-dimethyl-formamide at 50℃; for 12h;	98.1%

: 36865-41-5
3-bromopropanol methyl ether

: 603-35-0
triphenylphosphine

: 111088-69-8
(3-methoxypropyl)(triphenyl)phosphonium bromide

Conditions

Conditions	Yield
In toluene at 150℃; for 44h;	98%
In toluene at 150℃; for 24h;	96.9%
In toluene at 150℃; for 16h; Inert atmosphere;	91%

: 36865-41-5
3-bromopropanol methyl ether

: 16689-34-2
tert-butyl isopropylidenecarbazate

: 950859-79-7
N’isopropylidene-N-(3-methoxy-propyl)-hydrazinecarboxylic acid tert-butyl ester

Conditions

Conditions	Yield
With potassium hydroxide; tetra(n-butyl)ammonium hydrogensulfate In toluene at 50 - 80℃; for 3.75h;	98%
With tetra-(n-butyl)ammonium iodide; potassium hydroxide at 60℃;	70%

: 36865-41-5
3-bromopropanol methyl ether

: 1251583-07-9
C13H14N2O5

: 1251583-09-1
C17H22N2O6

Conditions

Conditions	Yield
Stage #1: C13H14N2O5 With caesium carbonate In dimethyl sulfoxide for 0.0833333h; Stage #2: 3-bromopropanol methyl ether In dimethyl sulfoxide at 20℃; for 18h;	98%

: 36865-41-5
3-bromopropanol methyl ether

: methyl 2-(2-(4-hydroxyphenyl)thiazol-4-yl)-2-methylpropanoate

: methyl 2-(2-(4-(3-methoxypropoxy)phenyl)thiazol-4-yl)-2-methylpropanoate

Conditions

Conditions	Yield
With potassium carbonate In acetone Reflux;	98%
With potassium carbonate In acetone Reflux;	98%
With potassium carbonate In acetone Reflux;	98%

: 36865-41-5
3-bromopropanol methyl ether

: 6-(4-bromophenyl)-4,4-dimethyl-4,5-dihydropyridazin-3(2H)-one

: 6-(4-bromophenyl)-2-(3-methoxypropyl)-4,4-dimethyl-4,5-dihydropyridazin-3(2H)-one

Conditions

Conditions	Yield
Stage #1: 6-(4-bromophenyl)-4,4-dimethyl-4,5-dihydropyridazin-3(2H)-one With sodium hydride In tetrahydrofuran at 0℃; for 0.5h; Stage #2: 3-bromopropanol methyl ether In tetrahydrofuran at 20℃;	98%

: 36865-41-5
3-bromopropanol methyl ether

: 1251582-90-7
C13H13BrN2O5

: 1251582-98-5
C17H21BrN2O6

Conditions

Conditions	Yield
Stage #1: C13H13BrN2O5 With caesium carbonate In dimethyl sulfoxide for 0.0833333h; Stage #2: 3-bromopropanol methyl ether In dimethyl sulfoxide at 20℃; for 18h;	97%

: 7-(benzyloxy)-1,2,3,4-tetrahydroquinoline

: 36865-41-5
3-bromopropanol methyl ether

: 943937-28-8
C20H25NO2

Conditions

Conditions	Yield
With sodium carbonate; potassium iodide In acetonitrile for 74h; Heating;	96%

: 36865-41-5
3-bromopropanol methyl ether

: 1251582-45-2
C18H13BrClNO4

: 1251584-49-2
C22H21BrClNO5

Conditions

Conditions	Yield
With caesium carbonate In dimethyl sulfoxide at 50℃; for 2h;	96%
With caesium carbonate In dimethyl sulfoxide at 20℃; for 2h; Inert atmosphere;	64%

: 2075-45-8
4-bromo-1H-pyrazole

: 36865-41-5
3-bromopropanol methyl ether

: 1183903-41-4
4-bromo-1-(3-methoxypropyl)-1H-pyrazole

Conditions

Conditions	Yield
With caesium carbonate In N,N-dimethyl-formamide at 50℃;	96%
With caesium carbonate In N,N-dimethyl-formamide at 20℃; for 8h;	94%
With caesium carbonate In N,N-dimethyl-formamide at 50℃;

: 36865-41-5
3-bromopropanol methyl ether

: 1234709-86-4
(R)-tert-butyl 3-(1H-benzo[d]imidazol-2-yl)piperidine-1-carboxylate

: 1365884-41-8
(R)-tert-butyl 3-(1-(3-methoxypropyl)-1H-benzo[d]imidazol-2-yl)piperidine-1-carboxylate

Conditions

Conditions	Yield
Stage #1: (R)-tert-butyl 3-(1H-benzo[d]imidazol-2-yl)piperidine-1-carboxylate With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0℃; for 0.5h; Inert atmosphere; Stage #2: 3-bromopropanol methyl ether In N,N-dimethyl-formamide; mineral oil at 0 - 20℃;	96%

: 36865-41-5
3-bromopropanol methyl ether

: 5-[(2S,3S)-1-tert-butoxycarbonyl-3-phenylpyrrolidine-2-carboxamide]-1H-indole-2-carboxylic acid

: 3-methoxypropyl 5-[(2S,3S)-1-tert-butoxycarbonyl-3-phenylpyrrolidine-2-carboxamide]-1H-indole-2-carboxylate

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 20℃;	96%

1-Bromo-3-methoxypropane Chemical Properties

Molecular Structure of 1-Bromo-3-methoxypropane (CAS NO.36865-41-5):

Empirical Formula: C₄H₉BrO
Molecular Weight: 153.0177
H bond acceptors: 1
H bond donors: 0
Freely Rotating Bonds: 3
Polar Surface Area: 9.23 Å²
Index of Refraction: 1.439
Molar Refractivity: 30.05 cm³
Molar Volume: 114.1 cm³
Surface Tension: 28.2 dyne/cm
Density: 1.341 g/cm³
Flash Point: 30.6 °C
Enthalpy of Vaporization: 32.84 kJ/mol
Boiling Point: 103.5 °C at 760 mmHg
Vapour Pressure: 37.2 mmHg at 25°C
Product Categories: Halides
SMILES: BrCCCOC
InChI: InChI=1/C4H9BrO/c1-6-4-2-3-5/h2-4H2,1H3

1-Bromo-3-methoxypropane Safety Profile

Hazard Codes: Xi
HazardClass: irritant

1-Bromo-3-methoxypropane Specification

1-Bromo-3-methoxypropane , with CAS number of 36865-41-5, can be called propane, 1-bromo-3-methoxy- ; 3-Bromopropyl methyl ether ; Ether,3-bromopropyl methyl (7CI) .

Product Name

1-Bromo-3-methoxypropane

Synthetic route

1-Bromo-3-methoxypropane Chemical Properties

1-Bromo-3-methoxypropane Safety Profile

1-Bromo-3-methoxypropane Specification

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