1-Methoxycarbonylamino-7-naphthol supplier

Name
1-Methoxycarbonylamino-7-naphthol
EINECS 205-070-8
CAS No. 132-63-8
Article Data3
CAS DataBase
Density 1.345 g/cm³
Solubility
Melting Point 51-52 °C
Formula C₁₂H₁₁NO₃
Boiling Point 361.9 °C at 760 mmHg
Molecular Weight 217.224
Flash Point 172.6 °C
Transport Information
Appearance grey powder
Safety
Risk Codes R20/21/22
Molecular Structure
Hazard Symbols Xn
Synonyms 1-Naphthalenecarbamicacid, 7-hydroxy-, methyl ester (6CI,8CI);Methyl N-(7-hydroxynaphthalen-1-yl)carbamate;Carbamic acid, (7-hydroxy-1-naphthalenyl)-, methyl ester;Methyl 7-hydroxy-1-naphthylcarbamate;
PSA 58.56000
LogP 2.79670

Synthetic route

: 118-46-7
8-amino-2-naphthol

: 79-22-1
methyl chloroformate

: 132-63-8
methyl 7-hydroxy-1-naphthylcarbamate

Conditions

Conditions	Yield
With pyridine for 0.75h;	100%

: 132-63-8
methyl 7-hydroxy-1-naphthylcarbamate

: 70615-55-3
8-isocyanato-2-naphthol

Conditions

Conditions	Yield
Stage #1: methyl 7-hydroxy-1-naphthylcarbamate With triethylamine In toluene for 0.166667h; Heating; Stage #2: With 2-chloro-1,3,2-benzodioxaborole In toluene for 0.25h; Further stages.;

: 132-63-8
methyl 7-hydroxy-1-naphthylcarbamate

: N-Phenyl-N'-<7-hydroxy-naphthyl-(1)>-harnstoff

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1.1: Et3N / toluene / 0.17 h / Heating 1.2: B-chlorocatecholborane / toluene / 0.25 h 2.1: toluene / 0.17 h / Heating View Scheme

: 132-63-8
methyl 7-hydroxy-1-naphthylcarbamate

: 1-(7-hydroxy-naphthalen-1-yl)-3-isopropyl-urea

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1.1: Et3N / toluene / 0.17 h / Heating 1.2: B-chlorocatecholborane / toluene / 0.25 h 2.1: toluene / 0.17 h / Heating View Scheme

: 132-63-8
methyl 7-hydroxy-1-naphthylcarbamate

: 1-(7-hydroxy-naphthalen-1-yl)-3-pyridin-3-yl-urea

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1.1: Et3N / toluene / 0.17 h / Heating 1.2: B-chlorocatecholborane / toluene / 0.25 h 2.1: toluene / 0.17 h / Heating View Scheme

: 132-63-8
methyl 7-hydroxy-1-naphthylcarbamate

: 1-(7-hydroxy-naphthalen-1-yl)-3-thiazol-2-yl-urea

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1.1: Et3N / toluene / 0.17 h / Heating 1.2: B-chlorocatecholborane / toluene / 0.25 h 2.1: toluene / 0.17 h / Heating View Scheme

: 132-63-8
methyl 7-hydroxy-1-naphthylcarbamate

: 1-(7-hydroxy-naphthalen-1-yl)-3-pyridin-2-yl-urea

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1.1: Et3N / toluene / 0.17 h / Heating 1.2: B-chlorocatecholborane / toluene / 0.25 h 2.1: toluene / 0.17 h / Heating View Scheme

: 132-63-8
methyl 7-hydroxy-1-naphthylcarbamate

: 1-(7-hydroxy-naphthalen-1-yl)-3-pyridin-4-yl-urea

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1.1: Et3N / toluene / 0.17 h / Heating 1.2: B-chlorocatecholborane / toluene / 0.25 h 2.1: toluene / 0.17 h / Heating View Scheme

: 132-63-8
methyl 7-hydroxy-1-naphthylcarbamate

: 1-benzyl-3-(7-hydroxy-naphthalen-1-yl)-urea

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1.1: Et3N / toluene / 0.17 h / Heating 1.2: B-chlorocatecholborane / toluene / 0.25 h 2.1: toluene / 0.17 h / Heating View Scheme

: 132-63-8
methyl 7-hydroxy-1-naphthylcarbamate

: 1-cyclopentyl-3-(7-hydroxy-naphthalen-1-yl)-urea

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1.1: Et3N / toluene / 0.17 h / Heating 1.2: B-chlorocatecholborane / toluene / 0.25 h 2.1: toluene / 0.17 h / Heating View Scheme

: 132-63-8
methyl 7-hydroxy-1-naphthylcarbamate

: 3282-30-2
pivaloyl chloride

: C17H19NO4

Conditions

Conditions	Yield
With triethylamine In dichloromethane at 0 - 20℃;

1-Methoxycarbonylamino-7-naphthol Specification

The Carbamic acid,N-(7-hydroxy-1-naphthalenyl)-, methyl ester with CAS registry number of 132-63-8 is also known as Methyl 7-hydroxy-1-naphthylcarbamate. The IUPAC name is Methyl N-(7-hydroxynaphthalen-1-yl)carbamate. Its EINECS registry number is 205-070-8. In addition, the formula is C₁₂H₁₁NO₃ and the molecular weight is 217.22.

Physical properties about Carbamic acid,N-(7-hydroxy-1-naphthalenyl)-, methyl ester are: (1)ACD/LogP: 2.26; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 2.26; (4)ACD/LogD (pH 7.4): 2.26; (5)ACD/BCF (pH 5.5): 30.89; (6)ACD/BCF (pH 7.4): 30.73; (7)ACD/KOC (pH 5.5): 405.56; (8)ACD/KOC (pH 7.4): 403.45; (9)#H bond acceptors: 4; (10)#H bond donors: 2; (11)#Freely Rotating Bonds: 3; (12)Index of Refraction: 1.694; (13)Molar Refractivity: 61.99 cm³; (14)Molar Volume: 161.4 cm³; (15)Surface Tension: 60.1 dyne/cm; (16)Density: 1.345 g/cm³; (17)Flash Point: 172.6 °C; (18)Enthalpy of Vaporization: 63.17 kJ/mol; (19)Boiling Point: 361.9 °C at 760 mmHg; (20)Vapour Pressure: 9.66E-06 mmHg at 25 °C.

Preparation of Carbamic acid,N-(7-hydroxy-1-naphthalenyl)-, methyl ester: it is prepared by reaction of carbonochloridic acid methyl ester with 8-amino-[2]naphthol. The reaction needs reagent pyridine for 45 minutes. The yield is about 100%.

Carbamic acid,N-(7-hydroxy-1-naphthalenyl)-, methyl ester is prepared by reaction of carbonochloridic acid methyl ester with 8-amino-[2]naphthol.

You can still convert the following datas into molecular structure:
1. Canonical SMILES: COC(=O)NC1=CC=CC2=C1C=C(C=C2)O
2. InChI: InChI=1S/C12H11NO3/c1-16-12(15)13-11-4-2-3-8-5-6-9(14)7-10(8)11/h2-7,14H,1H3,(H,13,15)
3. InChIKey: DZNFLGGCJZUMEM-UHFFFAOYSA-N

Product Name

1-Methoxycarbonylamino-7-naphthol

Synthetic route

1-Methoxycarbonylamino-7-naphthol Specification

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