2-(2-Furyl)-3-(5-nitro-2-furyl)acrylamide supplier

Name
2-(2-Furyl)-3-(5-nitro-2-furyl)acrylamide
EINECS
CAS No. 3688-53-7
Density 1.453g/cm³
Solubility

Stability

Stable. Hydrophobic.

Toxicology

Harmful if swallowed or inhaled. Experimental carcinogenand neoplastigen. Possible human carcinogen.

Toxicity data
(Th

Melting Point 151-152oC
Formula C11H8 N2 O5
Boiling Point 459.6°Cat760mmHg
Molecular Weight 248.195
Flash Point 231.8°C
Transport Information
Appearance orange crystalline solid
Safety Confirmed carcinogen with experimental carcinogenic, neoplastigenic, and teratogenic data. Poison by ingestion. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of NO_x.
Risk Codes
Molecular Structure
Hazard Symbols
Synonyms 2-Furanacrylamide,a-2-furyl-5-nitro- (7CI,8CI);2-(2-Furyl)-3-(5-nitro-2-furyl)acrylamide; 2-(2-Furyl)-3-(5-nitrofuryl)acrylamide;AF 2; AF 2 (preservative); Furylamide; Furylfuramide; NSC 44973
PSA 115.19000
LogP 3.03020

2-(2-Furyl)-3-(5-nitro-2-furyl)acrylamide Chemical Properties

IUPAC Name: 2-(Furan-2-yl)-3-(5-nitrofuran-2-yl)prop-2-enamide
The MF of 2-(2-Furyl)-3-(5-nitro-2-furyl)acrylamide (CAS NO.3688-53-7) is C₁₁H₈N₂O₅.

The MW of 2-(2-Furyl)-3-(5-nitro-2-furyl)acrylamide (CAS NO.3688-53-7) is 248.19.
Synonyms of 2-(2-Furyl)-3-(5-nitro-2-furyl)acrylamide (CAS NO.3688-53-7): Furylfuramide ; 2-Furanacetamide, alpha-((5-nitro-2-furanyl)methylene)- ; cis-3-(5-Nitro-2-furyl)-2-(2-furyl)acrylamide ; alpha-((5-nitro-2-furanyl)methylene)-2-furanacetamide
Apperance: Bright orange crystals
Stability: Stable. Hydrophobic
Index of Refraction: 1.641
Density: 1.453 g/ml
Flash Point: 231.8 °C
Boiling Point: 459.6 °C

2-(2-Furyl)-3-(5-nitro-2-furyl)acrylamide Uses

2-(2-Furyl)-3-(5-nitro-2-furyl)acrylamide (CAS NO.3688-53-7) is used as fine chemical raw materials, pharmaceutical intermediates, organic synthesis.

2-(2-Furyl)-3-(5-nitro-2-furyl)acrylamide Toxicity Data With Reference

1.	mmo-sat 4 µg/L	MUREAV Mutation Research. 147 (1985),219.
2.	sce-hmn:lym 500 µg/L	CNREA8 Cancer Research. 40 (1980),4775.
3.	scu-mus TDLo:150 mg/kg (13-17D preg):NEO,TER	NATUAS Nature. 258 (1975),610.
4.	orl-rat LD50:1554 mg/kg	TJEMAO Tohoku Journal of Experimental Medicine. 103 (1971),331.
5.	orl-mus LD50:221 mg/kg	NEZAAQ Nippon Eiseigaku Zasshi. Japanese Journal of Hygiene. 28 (1973),463.

2-(2-Furyl)-3-(5-nitro-2-furyl)acrylamide Consensus Reports

IARC Cancer Review: Group 2B IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 (1987),p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Human Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 31 (1983),p. 47.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 31 (1983),p. 47.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . EPA Genetic Toxicology Program.

2-(2-Furyl)-3-(5-nitro-2-furyl)acrylamide Safety Profile

Confirmed carcinogen with experimental carcinogenic, neoplastigenic, and teratogenic data. Poison by ingestion. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of NO_x.

2-(2-Furyl)-3-(5-nitro-2-furyl)acrylamide Specification

A nitrated amide. Organic amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P₂O₅ or SOCl₂ generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NO_x).

Product Name

2-(2-Furyl)-3-(5-nitro-2-furyl)acrylamide

Stability

Toxicology