2,2-Dimethoxyethylamine supplier

Name
2,2-Dimethoxyethylamine
EINECS 245-026-5
CAS No. 22483-09-6
Article Data16
CAS DataBase
Density 0.944 g/cm³
Solubility miscible with water
Melting Point -78oC
Formula C₄H₁₁NO₂
Boiling Point 133 °C at 760 mmHg
Molecular Weight 105.137
Flash Point 53.3 °C
Transport Information UN 1993 3/PG 3
Appearance clear colorless to pale yellow liquid
Safety 26-36/37/39-45-16-36
Risk Codes 10-34-36/37/38
Molecular Structure
Hazard Symbols C,F,Xi
Synonyms Acetaldehyde,amino-, dimethyl acetal (6CI,8CI);Ethylamine, 2,2-dimethoxy- (8CI);1-Amino-2,2-dimethoxyethane;Aminoacetaldehyde dimethyl acetal;
PSA 44.48000
LogP 0.26430

Synthetic route

: 97-97-2
chloroacetaldehyde dimethyl acetal

: 22483-09-6
2,2-dimethoxyethylamine

Conditions

Conditions	Yield
With ammonium hydroxide; carbon dioxide at 140℃; for 8h; Autoclave; Large scale;	94.2%
With methanol; ammonia at 140℃;
With ammonia at 20 - 70℃; under 15001.5 Torr; for 20h; Temperature; Pressure; Autoclave;	84.8 g

: 27328-34-3
2-(2,2-dimethoxyethyl)-1H-isoindole-1,3(2H)-dione

: 22483-09-6
2,2-dimethoxyethylamine

Conditions

Conditions	Yield
With ethanolamine at 170 - 180℃;	91%

: allyl 2,2-dimethoxyethylcarbamate

: 22483-09-6
2,2-dimethoxyethylamine

Conditions

Conditions	Yield
With tris(2,2'-bipyridine)nickel(II) tetrafluoroborate In tetrahydrofuran at 20℃; allyl carbamate cleavage; Electrochemical reaction; Zn/stainless steel couple electrodes; current intensity 60 mA; supporting electrolite: bis(trifluoromethylsulfonimide)Li;	60%

: 7252-83-7
1-bromo-2,2-dimethoxyethane

A: 56548-04-0
bis(dimethoxyethyl)amine

B: 22483-09-6
2,2-dimethoxyethylamine

Conditions

Conditions	Yield
With ethanol; ammonia at 140℃;
With ethanol; ammonia at 140℃; im Autoklaven;

: 5861-24-5
dimethoxy acetonitrile

: 22483-09-6
2,2-dimethoxyethylamine

Conditions

Conditions	Yield
With cyclohexane; ammonia; nickel at 90℃; under 66195.7 Torr; Hydrogenation;
With ammonia; nickel In methanol
With ammonia; nickel
With ammonia; nickel

: 22483-16-5
C8H17NO2

: 22483-09-6
2,2-dimethoxyethylamine

Conditions

Conditions	Yield
In water at 35℃; Equilibrium constant;

: Co(3+)*2(CCH3NO)2H(1-)*CH2CO2(2-)*(CH3O)2CHCH2NH2 = Co((CCH3NO)2H)2(CH2COO)(NH2CH2CH(OCH3)2)(1-)

: 778519-97-4
Co((CCH3NO)2H)2(CH2COO)H2O(1-)

B: 22483-09-6
2,2-dimethoxyethylamine

Conditions

Conditions	Yield
With KCl; H2O In water Kinetics; 25°C; not isolated, detected spectrophotometrically;

: Co(3+)*2(CCH3NO)2H(1-)*CH(CH3)CO2(2-)*(CH3O)2CHCH2NH2 = Co((CCH3NO)2H)2(CH(CH3)COO)(NH2CH2CH(OCH3)2)(1-)

: 786578-25-4
Co((CCH3NO)2H)2(CH(CH3)COO)H2O(1-)

B: 22483-09-6
2,2-dimethoxyethylamine

Conditions

Conditions	Yield
With KCl; H2O In water Kinetics; 25°C; not isolated, detected spectrophotometrically;

: 81956-67-4
(carboxymethyl)(2,2-dimethoxyethylamine)bis(dimethylglyoximato)cobalt(III)

: 60193-28-4
(carboxymethyl)aquocobaloxime

B: 22483-09-6
2,2-dimethoxyethylamine

Conditions

Conditions	Yield
With KCl; H2O In water Kinetics; 25°C; not isolated, detected spectrophotometrically;

: 81956-81-2
(1-carboxyethyl)(2,2-dimethoxyethylamine)bis(dimethylglyoximato)cobalt(III)

: 778519-97-4
Co((CCH3NO)2H)2(CH2COO)H2O(1-)

B: 22483-09-6
2,2-dimethoxyethylamine

Conditions

Conditions	Yield
With KCl; H2O In water Kinetics; 25°C; not isolated, detected spectrophotometrically;

: 1130734-52-9
1-benzyl-4-[(2,2-dimethoxyethyl)amino]-3,5-bis[(1S)-1-methoxyethyl]-4H-1,2,4-triazol-1-ium bromide

A: 1130734-54-1
1-benzyl-3,5-bis[(1S)-1-methoxyethyl]-4H-1,2,4-triazole

B: 22483-09-6
2,2-dimethoxyethylamine

Conditions

Conditions	Yield
With lithium borohydride In tetrahydrofuran

: 1345959-33-2
4-((2,2-dimethoxyethylcarbamoyloxy)methyl)-1-methylpyridinium trifluoromethanesulfonate

A: 22483-09-6
2,2-dimethoxyethylamine

B: 1,4-dimethylpyridin-1-ium trifluoromethanesulfonate

Conditions

Conditions	Yield
With tris(2,2'-bipyridyl)ruthenium dichloride; ascorbic acid In d(4)-methanol for 4h; Photolysis; Inert atmosphere;	A 99 %Spectr. B n/a

: 13679-70-4
5-methylthiophene-2-carboxaldehyde

: 22483-09-6
2,2-dimethoxyethylamine

: 890148-08-0
(2,2-Dimethoxy-ethyl)-[1-(5-methyl-thiophen-2-yl)-meth-(E)-ylidene]-amine

Conditions

Conditions	Yield
at 0℃; for 0.5h;	100%
With toluene-4-sulfonic acid In ethanol for 2h; Heating;

: 7797-83-3
2H-benzo[d]1,3-dioxolane-4-carbaldehyde

: 22483-09-6
2,2-dimethoxyethylamine

: 29544-25-0
2,3-methylenedioxybenzylaminoacetaldehyde dimethylacetal

Conditions

Conditions	Yield
With hydrogen; platinum(IV) oxide In ethanol for 24h;	100%

: 104-87-0
4-methyl-benzaldehyde

: 22483-09-6
2,2-dimethoxyethylamine

: 54879-70-8
(2,2-Dimethoxy-ethyl)-[1-p-tolyl-meth-(Z)-ylidene]-amine

Conditions

Conditions	Yield
at 70 - 190℃;	100%
for 0.333333h; Heating;
In chloroform at 22 - 65℃;
In chloroform at 90℃;

: 104-88-1
4-chlorobenzaldehyde

: 22483-09-6
2,2-dimethoxyethylamine

: 54879-73-1
N-<(4-chlorophenyl)methylene>-2,2-dimethoxyethanamine

Conditions

Conditions	Yield
In toluene for 1.5h; Heating;	100%
for 0.333333h; Heating;

: 104-88-1
4-chlorobenzaldehyde

: 22483-09-6
2,2-dimethoxyethylamine

: 54879-73-1
[1-(4-Chloro-phenyl)-meth-(Z)-ylidene]-(2,2-dimethoxy-ethyl)-amine

Conditions

Conditions	Yield
In benzene Heating;	100%
In toluene Heating;

: 89-98-5
2-chloro-benzaldehyde

: 22483-09-6
2,2-dimethoxyethylamine

: 62882-12-6
N-<(2-chlorophenyl)methylene>-2,2-dimethoxyethanamine

Conditions

Conditions	Yield
In toluene for 1.5h; Heating;	100%
In benzene
for 0.333333h; Heating;

: 89-98-5
2-chloro-benzaldehyde

: 22483-09-6
2,2-dimethoxyethylamine

: 62882-12-6
[1-(2-Chloro-phenyl)-meth-(Z)-ylidene]-(2,2-dimethoxy-ethyl)-amine

Conditions

Conditions	Yield
In benzene Heating;	100%

: 86-81-7
3,4,5-trimethoxy-benzaldehyde

: 22483-09-6
2,2-dimethoxyethylamine

: 39964-85-7
2,2-dimethoxy-N-<(3',4',5'-trimethoxyphenyl)methylene>ethylamine

Conditions

Conditions	Yield
In benzene for 5.25h; Heating;	100%
With magnesium sulfate In chloroform at 20℃; for 24h;	100%
With magnesium sulfate In chloroform at 20℃; for 24h;	100%

: 874-42-0
2,4-dichlorobenzaldeyhde

: 22483-09-6
2,2-dimethoxyethylamine

: [1-(2,4-Dichloro-phenyl)-meth-(Z)-ylidene]-(2,2-dimethoxy-ethyl)-amine

Conditions

Conditions	Yield
In benzene Heating;	100%

: 120-14-9
3,4-dimethoxy-benzaldehyde

: 22483-09-6
2,2-dimethoxyethylamine

: 39964-87-9
N-(2,2-dimethoxyethyl)-1-(3,4-dimethoxyphenyl)methanimine

Conditions

Conditions	Yield
In benzene for 4h; Heating;	100%
With magnesium sulfate In chloroform at 20℃; for 24h;	100%
In benzene for 4h; Reflux;	99.1%

: 587-04-2
3-Chlorobenzaldehyde

: 22483-09-6
2,2-dimethoxyethylamine

: 62882-13-7
N-<(3-chlorophenyl)methylene>-2,2-dimethoxyethanamine

Conditions

Conditions	Yield
In toluene for 1.5h; Heating;	100%
In benzene
for 0.333333h; Heating;

: 6334-18-5
2,3-dichlorobenzylaldehyde

: 22483-09-6
2,2-dimethoxyethylamine

: 57987-75-4
N-<(2,3-dichlorophenyl)methylene>-2,2-dimethoxyethanamine

Conditions

Conditions	Yield
In toluene for 1.5h; Heating;	100%
In toluene for 0.5h; Heating;	100%
for 0.333333h; Heating;

: 6334-18-5
2,3-dichlorobenzylaldehyde

: 22483-09-6
2,2-dimethoxyethylamine

: 57987-75-4
2,3-dichloro-N-(2,2-dimethoxyethyl)benzylidenamine

Conditions

Conditions	Yield
In benzene Heating;	100%
In toluene

: 93-02-7
2,5-dimethoxybenzaldehyde

: 22483-09-6
2,2-dimethoxyethylamine

: 54879-66-2
acetaldehyde dimethyl acetal

Conditions

Conditions	Yield
In toluene Heating;	100%
In toluene for 4h; Heating;	100%
With magnesium sulfate In chloroform at 20℃; for 24h;	100%
With magnesium sulfate In chloroform at 20℃; for 24h;	100%
In toluene for 4h; Reflux; Dean-Stark;

: 624-83-9
methyl isocyanate

: 22483-09-6
2,2-dimethoxyethylamine

: 115869-17-5
N-(2,2-dimethoxyethyl)-N-methylurea

Conditions

Conditions	Yield
In benzene	100%

: 98-59-9
p-toluenesulfonyl chloride

: 22483-09-6
2,2-dimethoxyethylamine

: 58754-95-3
N-(2,2-dimethoxyethyl)-p-toluenesulfonamide

Conditions

Conditions	Yield
With triethylamine In dichloromethane at 0℃; for 0.5h;	100%
With triethylamine In dichloromethane at 0 - 20℃; Inert atmosphere;	100%
With triethylamine In dichloromethane	100%

: 6287-38-3
3,4-dichlorobenzaldehyde

: 22483-09-6
2,2-dimethoxyethylamine

: 73274-27-8
N-<(3,4-dichlorophenyl)methylene>-2,2-dimethoxyethanamine

Conditions

Conditions	Yield
In toluene for 1.5h; Heating;	100%
In toluene for 0.5h; Heating;	100%
for 0.333333h; Heating;

: 6287-38-3
3,4-dichlorobenzaldehyde

: 22483-09-6
2,2-dimethoxyethylamine

: 73274-27-8
[1-(3,4-Dichloro-phenyl)-meth-(Z)-ylidene]-(2,2-dimethoxy-ethyl)-amine

Conditions

Conditions	Yield
In benzene Heating;	100%
In toluene Heating / reflux;

: 6361-23-5
2,5-dichloro-benzaldehyde

: 22483-09-6
2,2-dimethoxyethylamine

: [1-(2,5-Dichloro-phenyl)-meth-(Z)-ylidene]-(2,2-dimethoxy-ethyl)-amine

Conditions

Conditions	Yield
In benzene Heating;	100%

: 59938-06-6, 17129-06-5
4-ethoxy-1,1,1-trifluoro-3-butene-2-one

: 22483-09-6
2,2-dimethoxyethylamine

: 144219-77-2
1,1,1-trifluoro-4-(2,2-dimethoxyethylamino)-3-buten-2-one

Conditions

Conditions	Yield
In acetonitrile for 4h; Ambient temperature;	100%

: 5779-91-9
2,3-bis(benzyloxy)benzaldehyde

: 22483-09-6
2,2-dimethoxyethylamine

: 92366-92-2
2-amino>acetaldehyde dimethyl acetal

Conditions

Conditions	Yield
In benzene for 3.5h; Heating;	100%

: 10203-08-4
3,5-dichlorobenzaldehyde

: 22483-09-6
2,2-dimethoxyethylamine

: [1-(3,5-Dichloro-phenyl)-meth-(Z)-ylidene]-(2,2-dimethoxy-ethyl)-amine

Conditions

Conditions	Yield
In benzene Heating;	100%

: 19361-59-2
2,3,4-trichlorobenzaldehyde

: 22483-09-6
2,2-dimethoxyethylamine

: (2,2-Dimethoxy-ethyl)-[1-(2,3,4-trichloro-phenyl)-meth-(Z)-ylidene]-amine

Conditions

Conditions	Yield
In benzene Heating;	100%

: 60277-96-5
2-allyl-2-hydroxycyclohexanone

: 22483-09-6
2,2-dimethoxyethylamine

: 128939-15-1
1-Allyl-2-[(E)-2,2-dimethoxy-ethylimino]-cyclohexanol

Conditions

Conditions	Yield
In toluene Heating;	100%

: 109773-81-1
(3Z)-4-ethoxy-1,1,1-trifluoro-4-phenylbut-3-en-2-one

: 22483-09-6
2,2-dimethoxyethylamine

: 144219-78-3
1,1,1-trifluoro-4-(2,2-dimethoxyethylamino)-4-phenyl-3-buten-2-one

Conditions

Conditions	Yield
In acetonitrile for 4h; Ambient temperature;	100%

: 135351-20-1, 102145-82-4
1,1,1-trifluoro-4-methoxypent-3-en-2-one

: 22483-09-6
2,2-dimethoxyethylamine

: 142991-73-9
1,1,1-trifluoro-4-(2,2-dimethoxyethylamino)-3-penten-2-one

Conditions

Conditions	Yield
In acetonitrile for 4h; Ambient temperature;	100%

: 85071-59-6
1-bromo-2,3,5-trimethoxy-4-methylbenzaldehyde

: 22483-09-6
2,2-dimethoxyethylamine

: 94893-31-9
2,2-dimethoxy-N-(2,3,5-trimethoxy-4-methylbenzylidene)ethylamine

Conditions

Conditions	Yield
In benzene Heating;	100%

: 95333-92-9
3-(3,5-difluorophenyl)propanoyl chloride

: 22483-09-6
2,2-dimethoxyethylamine

: 95333-93-0
3-(3,5-difluorophenyl)-N-(2,2-dimethoxyethyl)propionamide

Conditions

Conditions	Yield
In dichloromethane at 0℃; for 1h;	100%

: 22483-09-6
2,2-dimethoxyethylamine

: 109-90-0
ethyl isocyanate

: 115869-18-6
N-(2,2-dimethoxyethyl)-N-ethylurea

Conditions

Conditions	Yield
In benzene	100%

: 22483-09-6
2,2-dimethoxyethylamine

: 456-48-4
3-Fluorobenzaldehyde

: 73261-94-6
N-<(3-fluorophenyl)methylene>-2,2-dimethoxyethanamine

Conditions

Conditions	Yield
In toluene for 1.5h; Heating;	100%
for 0.333333h; Heating;
In benzene Reflux;

2,2-Dimethoxyethylamine Chemical Properties

Product Name: Aminoacetaldehyde dimethyl acetal (CAS NO.22483-09-6)

Molecular Formula: C₄H₁₁NO₂
Molecular Weight: 105.14g/mol
Mol File: 22483-09-6.mol
EINECS: 245-026-5
Appearance: Clear colorless to pale yellow liquid
Boiling point: 135-139 °C 95 mm Hg(lit.)
Storage Temperature: Flammables area
Flash Point: 128 °F
Density: 0.965 g/mL at 25 °C(lit.)
Refractive index: n20/D 1.417(lit.)
Surface Tension: 28.4 dyne/cm
Enthalpy of Vaporization: 37.05 kJ/mol
Vapour Pressure: 8.66 mmHg at 25°C
XLogP3-AA: -0.8
H-Bond Donor: 1
H-Bond Acceptor: 3
Structure Descriptors of Aminoacetaldehyde dimethyl acetal (CAS NO.22483-09-6):
IUPAC Name: 2,2-dimethoxyethanamine
Canonical SMILES: COC(CN)OC
InChI: InChI=1S/C4H11NO2/c1-6-4(3-5)7-2/h4H,3,5H2,1-2H3
InChIKey: QKWWDTYDYOFRJL-UHFFFAOYSA-N
Product Categories: Pharmaceutical Intermediates

2,2-Dimethoxyethylamine Safety Profile

Safety Information of Aminoacetaldehyde dimethyl acetal (CAS NO.22483-09-6):
Hazard Codes: C Corrosive ,F,Xi Irritant
Risk Statements: 10-34-36/37/38
R10: Flammable
R34: Causes burns
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36/37/39-45-16-36
S16: Keep away from sources of ignition - No smoking
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
S45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
RIDADR: UN 1993 3/PG 3
WGK Germany: 2
Hazard Note: Flammable/Corrosive
HazardClass: 3
PackingGroup: III
HS Code: 29225000

2,2-Dimethoxyethylamine Specification

2,2-Dimethoxyethylamine , its CAS NO. is 22483-09-6, the synonyms are Acetaldehyde,amino-, dimethyl acetal (6CI,8CI) ; Ethylamine, 2,2-dimethoxy- (8CI) ; 1-Amino-2,2-dimethoxyethane ; 2,2-Dimethoxyethanamine .

Product Name

2,2-Dimethoxyethylamine

Synthetic route

2,2-Dimethoxyethylamine Chemical Properties

2,2-Dimethoxyethylamine Safety Profile

2,2-Dimethoxyethylamine Specification

Related Products

Hot Products