2-Amino-4-chloro-6-methylpyrimidine

The 2-Amino-4-chloro-6-methylpyrimidine with the cas number 5600-21-5. It is also called (1)2-Pyrimidinamine, 4-chloro-6-methyl- (9CI) ; (2)4-Chloro-6-methylpyrimidin-2-ylamine ; (3)Pyrimidine, 2-amino-4-chloro-6-methyl- . It belongs to the following product categories: (1)Pyrimidine; (2)Fine Chemical&intermediates; (3)Fluorobenzene; (4)Amines; (5)Pyrazines, Pyrimidines & Pyridazines; (6)Pyrimidines; (7)Building Blocks; (8)Halogenated Heterocycles; (9)Heterocyclic Building Blocks; (10)PyrimidinesHeterocyclic Building Blocks.

Properties of 2-Amino-4-chloro-6-methylpyrimidine : (1)ACD/LogP: 0.75 ; (2)# of Rule of 5 Violations: 0 ; (3)ACD/LogD (pH 5.5): 0.751 ; (4)ACD/LogD (pH 7.4): 0.753 ; (5)ACD/BCF (pH 5.5): 2.191 ; (6)ACD/BCF (pH 7.4): 2.199 ; (7)ACD/KOC (pH 5.5): 60.938 ; (8)ACD/KOC (pH 7.4): 61.184 ; (9)#H bond acceptors: 3 ; (10)#H bond donors: 2 ; (11)#Freely Rotating Bonds: 0 ; (12)Polar Surface Area: 51.8 Å² ; (13)Index of Refraction: 1.6 ; (14)Molar Refractivity: 36.391 cm³ ; (15)Molar Volume: 106.387 cm³ ; (16)Polarizability: 14.427 ×10^-24cm³ ; (17)Surface Tension: 59.053 dyne/cm ; (18)Density: 1.35 g/cm³ ; (19)Flash Point: 150.965 °C ; (20)Enthalpy of Vaporization: 56.818 kJ/mol ; (21)Boiling Point: 326.009 °C at 760 mmHg ; (22)Vapour Pressure: 0 mmHg at 25°C

The 2-Amino-4-hydroxy-6-methylpyrimidine seems like white to light yellow needle-like cryst powder. It is quite irritating to eyes, respiratory system and skin. When you are using this chemical, please wear suitable gloves and eye/face protection to avoid contact with skin and eyes. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Besides, Do not breathe dust, because it is quite harmful by inhalation, in contact with skin and if swallowed.

The 2-Amino-4-hydroxy-6-methylpyrimidine can react with 3-bromo-2-oxo-propionic acid ethyl ester to obtained 5-chloro-7-methyl-imidazo[1,2-a]pyrimidine-2-carboxylic acid ethyl ester with heating for 48 hour(s). Yield is 48 % .



You can still convert the following datas into molecular structure :
1.SMILES:Cc1cc(nc(n1)N)Cl
2.InChI:InChI=1/C5H6ClN3/c1-3-2-4(6)9-5(7)8-3/h2H,1H3,(H2,7,8,9)