2-Aminothiazole

First Aid Measures:
Ingestion:Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Skin:Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Eyes:Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Storage:Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Hormones and antibiotics room. Refrigerator (approx 4 C).
Handling:Wash thoroughly after handling. Wash hands before eating. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Do not breathe dust, vapor, mist, or gas. Keep container tightly closed. Do not ingest or inhale.

The 2-Aminothiazole, with the CAS registry number 96-50-4, is also known as 2-Thiazolylamine. It belongs to the product categories of Sulphur Derivatives; Thiazoles. Its EINECS number is 202-511-6. This chemical's molecular formula is C₃H₄N₂S and molecular weight is 100.14. What's more, its systematic name is 1,3-Thiazol-2-amine. Its classification codes are: (1)Drug / Therapeutic Agent; (2)Mutation data. It should be sealed and stored in a cool and ventilated place. Moreover, it should be protected from oxides, heat and fire. This chemical is used as as pharmaceutical intermediates, and it is also used in organic synthesis.

Physical properties of 2-Aminothiazole are: (1)ACD/LogP: 0.001; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -0.11; (4)ACD/LogD (pH 7.4): 0.00; (5)ACD/BCF (pH 5.5): 1.00; (6)ACD/BCF (pH 7.4): 1.00; (7)ACD/KOC (pH 5.5): 18.70; (8)ACD/KOC (pH 7.4): 23.76; (9)#H bond acceptors: 2; (10)#H bond donors: 2; (11)#Freely Rotating Bonds: 0; (12)Polar Surface Area: 67.15 Å²; (13)Index of Refraction: 1.645; (14)Molar Refractivity: 26.965 cm³; (15)Molar Volume: 74.417 cm³; (16)Polarizability: 10.69×10^-24cm³; (17)Surface Tension: 63.92 dyne/cm; (18)Density: 1.346 g/cm³; (19)Flash Point: 84.666 °C; (20)Enthalpy of Vaporization: 45.274 kJ/mol; (21)Boiling Point: 216.383 °C at 760 mmHg; (22)Vapour Pressure: 0.14 mmHg at 25°C.

Preparation of 2-Aminothiazole: this chemical can be prepared by thiourea and 1,2-dichloro-1-ethoxy-ethane. It is a reaction of hantzsch thiazole synthesis. The yield is about 90%.

Uses of 2-Aminothiazole: it can be used to produce N-thiazol-2-yl-succinamic acid by heating. It will need solvent acetone with the reaction time of 6 hours. The yield is about 94%.

When you are using this chemical, please be cautious about it as the following:
This chemical is harmful by inhalation, in contact with skin and if swallowed. It is irritating to eyes and respiratory system. In case of contact with eyes, you should rinse immediately with plenty of water and seek medical advice. When using it, you need wear suitable protective clothing, gloves and eye/face protection.

You can still convert the following datas into molecular structure:
(1)SMILES: c1csc(n1)N
(2)Std. InChI: InChI=1S/C3H4N2S/c4-3-5-1-2-6-3/h1-2H,(H2,4,5)
(3)Std. InChIKey: RAIPHJJURHTUIC-UHFFFAOYSA-N

The toxicity data is as follows: