2-Fluoro-5-methylaniline

The 2-Fluoro-5-methylaniline, with the CAS registry number 452-84-6, is also known as 3-Amino-4-fluorotoluene. It belongs to the product categories of Fluorin-Contained Toluene Series;Anilines, Aromatic Amines and Nitro Compounds; Aniline; Aniline Series. This chemical's molecular formula is C₇H₈FN and molecular weight is 125.14. What's more, its IUPAC name is the same with its product name. It should be kept in a cold and dry place.

Physical properties about 2-Fluoro-5-methylaniline are: (1)ACD/LogP: 1.73; (2)# of Rule of 5 Violations: 0; (3)#H bond acceptors: 1; (4)#H bond donors: 2; (5)#Freely Rotating Bonds: 1; (6)Polar Surface Area: 3.24 Å²; (7)Index of Refraction: 1.541; (8)Molar Refractivity: 35.3 cm³; (9)Molar Volume: 112.1 cm³; (10)Surface Tension: 37.6 dyne/cm; (11)Density: 1.115 g/cm³; (12)Flash Point: 81.7 °C; (13)Enthalpy of Vaporization: 43.77 kJ/mol; (14)Boiling Point: 201.5 °C at 760 mmHg; (15)Vapour Pressure: 0.307 mmHg at 25 °C.

Uses of 2-Fluoro-5-methylaniline: it is used to produce other chemicals. For example, it can react with 2-Bromo-3-nitro-benzoic acid to get 2-(2-Fluoro-5-methyl-phenylamino)-3-nitro-benzoic acid. The reaction occurs with reagents Cu, cuprous chloride, N-ethylmorpholine for 18 hours. The yield is 70 %.

When you are dealing with this chemical, you should be very careful. This chemical is toxic by inhalation, in contact with skin and if swallowed. It is irritating to eyes, respiratory system and skin. Therefore, you could take off immediately all contaminated clothing. And you should wear suitable protective clothing, gloves and eye/face protection. In case of contacting with eyes, you should rinse immediately with plenty of water and seek medical advice.

You can still convert the following datas into molecular structure:
(1) SMILES: Fc1ccc(cc1N)C
(2) InChI: InChI=1S/C7H8FN/c1-5-2-3-6(8)7(9)4-5/h2-4H,9H2,1H3
(3) InChIKey: QZUXMXZNVAJNSE-UHFFFAOYSA-N