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Name
PHENMETRAZINE HYDROCHLORIDE CII (200 MG)
- EINECS
- CAS No. 1707-14-8
- Article Data3
- CAS DataBase
- Density g/cm3
- Solubility
- Melting Point 175-177°C
- Formula C11H15 N O . Cl H
- Boiling Point 285.2°Cat760mmHg
- Molecular Weight 213.707
- Flash Point 112.7°C
- Transport Information
- Appearance
- Safety Poison by ingestion, intravenous, intraperitoneal, and subcutaneous routes. Human reproductive effects. Human teratogenic effects by ingestion: developmental abnormalities of the respiratory and gastrointestinal systems, and effects on newborn including neonatal measures or effects. When heated to decomposition it emits very toxic fumes of NOx and HCl.
- Risk Codes
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Molecular Structure
- Hazard Symbols
- Synonyms Morpholine,3-methyl-2-phenyl-, hydrochloride (6CI,8CI,9CI);2-Phenyl-3-methyltetrahydro-1,4-oxazine hydrochloride;3-Methyl-2-phenylmorpholine hydrochloride; Marsine; Mefolin; Neo-Zine;Phenmetrazine hydrochloride; Preludin; Preludin hydrochloride
- PSA 21.26000
- LogP 2.86680
3-Methyl-2-phenylmorpholine hydrochloride Chemical Properties
IUPAC Name: 3-methyl-2-phenylmorpholine hydrochloride
Synonyms of 3-Methyl-2-phenylmorpholine hydrochloride (CAS NO.1707-14-8): Phenmetrazine Hydrochloride [USAN] ; 2-Phenyl-3-methyltetrahydro-1,4-oxazine hydrochloride ; 3-Methyl-2-phenyltetrahydro-2H-1,4-oxazine hydrochloride ; A 66 hydrochloride ; EINECS 216-950-6 ; Marsin ; Mefolin ; NSC 405728 ; Neo-zine ; Phenmetrazine hydrochloride ; Preludin ; Probese-P hydrochloride ; Psychamine A 66 hydrochloride ; UNII-6U85YRT588 ; USAF GE-1 ; Morpholine, 3-methyl-2-phenyl-, hydrochloride ; DEA No. 1631 ; Preludin
CAS NO: 1707-14-8
Molecular Formula of 3-Methyl-2-phenylmorpholine hydrochloride (CAS NO.1707-14-8): C11H16ClNO
Molecular Weight: 213.7038
Molecular Structure:
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H bond acceptors: 2
H bond donors: 1
Freely Rotating Bonds: 1
Polar Surface Area: 12.47 Å2
Flash Point of 3-Methyl-2-phenylmorpholine hydrochloride (CAS NO.1707-14-8): 112.7 °C
Enthalpy of Vaporization: 52.43 kJ/mol
Boiling Point: 285.2 °C at 760 mmHg
Vapour Pressure: 0.00284 mmHg at 25°C
3-Methyl-2-phenylmorpholine hydrochloride Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intraperitoneal | 50mg/kg (50mg/kg) | National Technical Information Service. Vol. AD277-689, | |
| mouse | LD50 | intravenous | 71mg/kg (71mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Toxicology and Applied Pharmacology. Vol. 2, Pg. 589, 1960. |
| mouse | LD50 | oral | 165mg/kg (165mg/kg) | SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS SKIN AND APPENDAGES (SKIN): HAIR: OTHER | Arzneimittel-Forschung. Drug Research. Vol. 13, Pg. 711, 1963. |
| mouse | LD50 | subcutaneous | 240mg/kg (240mg/kg) | SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE BEHAVIORAL: EXCITEMENT SKIN AND APPENDAGES (SKIN): HAIR: OTHER | Acta Pharmaceutica Suecica. Vol. 4, Pg. 37, 1967. |
| rabbit | LD50 | intravenous | 41mg/kg (41mg/kg) | "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 286, 1972. | |
| rat | LD50 | intraperitoneal | 175mg/kg (175mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Toxicology and Applied Pharmacology. Vol. 2, Pg. 589, 1960. |
| rat | LD50 | oral | 165mg/kg (165mg/kg) | SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS SKIN AND APPENDAGES (SKIN): HAIR: OTHER | Arzneimittel-Forschung. Drug Research. Vol. 13, Pg. 711, 1963. |
| rat | LD50 | subcutaneous | 350mg/kg (350mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Toxicology and Applied Pharmacology. Vol. 2, Pg. 589, 1960. |
3-Methyl-2-phenylmorpholine hydrochloride Safety Profile
RIDADR: 3249
HazardClass: 6.1(b)
PackingGroup: III
Poison by ingestion, intravenous, intraperitoneal, and subcutaneous routes. Human reproductive effects. Human teratogenic effects by ingestion: developmental abnormalities of the respiratory and gastrointestinal systems, and effects on newborn including neonatal measures or effects. When heated to decomposition it emits very toxic fumes of NOx and HCl.
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