3-ETHYL-3-METHYLGLUTARIMIDE

Molecule structure of 3-Methyl-3-ethylglutarimide (CAS NO.64-65-3) :

IUPAC Name: 4-ethyl-4-methylpiperidine-2,6-dione 
Molecular Weight: 155.19432 g/mol
Molecular Formula: C₈H₁₃NO₂ 
Density: 1.024 g/cm³ 
Melting Point: 126.5 deg C
Boiling Point: 282 °C at 760 mmHg 
Flash Point: 125.8 °C
Appreance: white to off-white flakes or powder
Molar Volume: 151.4 cm³
Polarizability: 16.09*10^-24 cm³
Surface Tension: 30.4 dyne/cm 
Enthalpy of Vaporization: 52.09 kJ/mol
Vapour Pressure: 0.00344 mmHg at 25 °C 
log P (octanol-water): 0.520
Atmospheric OH Rate Constant: 8.71E-12 cm³/molecule-sec
XLogP3-AA: 0.7
H-Bond Donor: 1
H-Bond Acceptor: 2
Rotatable Bond Count: 1
Tautomer Count: 2
Exact Mass: 155.094629
MonoIsotopic Mass: 155.094629
Topological Polar Surface Area: 46.2
Heavy Atom Count: 11
Complexity: 182
Canonical SMILES: CCC1(CC(=O)NC(=O)C1)C
InChI: InChI=1S/C8H13NO2/c1-3-8(2)4-6(10)9-7(11)5-8/h3-5H2,1-2H3,(H,9,10,11)
InChIKey: ORRZGUBHBVWWOP-UHFFFAOYSA-N
EINECS: 200-588-0 
Storage temp.: −20 °C
Merck: 1027

 3-Methyl-3-ethylglutarimide (CAS NO.64-65-3) is central stimulant medicine. 3-Methyl-3-ethylglutarimide is mainly used for lifting poisoning of barbiturates, guided sleep energy, chloral hydrate and other drugs. It is also used to reduce sodium Thiopental the depth of anesthesia in order to expedite their recovery.

Reported in EPA TSCA Inventory.

Poison by ingestion, intravenous, intraperitoneal, intramuscular, subcutaneous, and parenteral routes. Human systemic effects by ingestion: wakefulness, hallucinations, distorted perceptions, toxic psychosis. An analeptic, central nervous system stimulant; used to counteract barbiturate poisoning. When heated to decomposition it emits toxic fumes of NO_x.
Hazard Codes: T
Risk Statements: 23/24/25
R23/24/25: Toxic by inhalation, in contact with skin and if swallowed
Safety Statements: 22-36/37/39-45 
S22:Do not breathe dust 
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible)
RIDADR: UN 2811 6.1/PG 2
WGK Germany: 3
RTECS: MA4550000
HazardClass: 6.1(a)
PackingGroup: II

 3-Methyl-3-ethylglutarimide (CAS NO.64-65-3) is also called 2,6-Dioxo-4-methyl-4-ethylpiperidine ; 3-Ethyl-3-methylglutarimide ; 4-Ethyl-4-methyl-2,6-dioxopiperidine ; 4-Ethyl-4-methyl-2,6-piperidinedione ; 4-Methyl-4-ethyl-2,6-dioxopiperidine ; Bemegrida [INN-Spanish] ; Bemegride ; Bemegridum [INN-Latin] ; beta-Ethyl-beta-methylglutarimide ; beta-Methyl-beta-ethylglutarimide . 3-Methyl-3-ethylglutarimide (CAS NO.64-65-3) is insoluble in water. 3-Methyl-3-ethylglutarimide (CAS NO.64-65-3) is an amide. Amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P₂O₅ or SOCl₂ generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx). When heated to decomposition 3-Methyl-3-ethylglutarimide emits toxic fumes. Flash point data for 3-Methyl-3-ethylglutarimide are not available. 3-Methyl-3-ethylglutarimide is probably not flammable.