Product Name

  • Name

    ACECLIDINE HYDROCHLORIDE

  • EINECS
  • CAS No. 6109-70-2
  • Density
  • Solubility
  • Melting Point 166°C
  • Formula C9H15 N O2 . Cl H
  • Boiling Point 221.5°C at 760 mmHg
  • Molecular Weight 205.71
  • Flash Point 85°C
  • Transport Information
  • Appearance
  • Safety Poison by intraperitoneal and intravenous routes. When heated to decomposition it emits very toxic fumes of NOx and HCl. See also ESTERS.
  • Risk Codes
  • Molecular Structure Molecular Structure of 6109-70-2 (ACECLIDINE HYDROCHLORIDE)
  • Hazard Symbols
  • Synonyms 1-Azabicyclo[2.2.2]octan-3-ol,acetate (ester), hydrochloride (9CI); 3-Quinuclidinol, acetate (ester),hydrochloride (8CI); 3-Quinuclidinol, acetate, hydrochloride (7CI); (?à)-3-Acetoxyquinuclidinehydrochloride; 3-Acetoxyquinuclidine hydrochloride; Aceclidine hydrochloride;Glaucostat
  • PSA 29.54000
  • LogP 1.38360

3-Quinclidinol dl-form acetate hydrochloride Chemical Properties

IUPAC Name: 1-Azabicyclo[2.2.2]octan-8-yl acetate hydrochloride
Synonyms of 3-Quinclidinol dl-form acetate hydrochloride (CAS NO.6109-70-2): 1-Azabicyclo(2.2.2)octan-3-ol, acetate (ester), hydrochloride ; 3-Acetoxyquinuclidine hydrochloride ; Aceclidine hydrochloride ; Glaucostat  ; Quinuclidin-3-yl acetate hydrochloride
CAS NO: 6109-70-2
Molecular Formula: C9H16ClNO2
Molecular Weight: 205.6818
Molecular Structure:
EINECS: 228-071-5
H bond acceptors: 3
H bond donors: 0
Freely Rotating Bonds: 2
Polar Surface Area: 29.54 Å2
Index of Refraction:
Molar Refractivity: cm3
Molar Volume: cm3
Surface Tension: dyne/cm
Density: g/cm3
Flash Point: 85 °C 
Melting Point: 166°C
Enthalpy of Vaporization: 45.79 kJ/mol
Boiling Point: 221.5 °C at 760 mmHg
Vapour Pressure: 0.107 mmHg at 25°
Appearance: 3-Quinclidinol dl-form acetate hydrochloride (CAS NO.6109-70-2) is white crystalline powder.
Product Categories: Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
InChI: InChI=1/C9H15NO2.ClH/c1-7(11)12-9-6-10-4-2-8(9)3-5-10;/h8-9H,2-6H2,1H3;1H
InChIKey: LWWSARSTZGNKGV-UHFFFAOYAN
Std. InChI: InChI=1S/C9H15NO2.ClH/c1-7(11)12-9-6-10-4-2-8(9)3-5-10;/h8-9H,2-6H2,1H3;1H
Std. InChIKey: LWWSARSTZGNKGV-UHFFFAOYSA-N

3-Quinclidinol dl-form acetate hydrochloride Uses

 3-Quinclidinol dl-form acetate hydrochloride (CAS NO.6109-70-2) is a synthetic analogue of arecoline, a natural cholinomimetic alkaloid. Aceclidine acts as an agonist at cholinergic receptors and has therapeutic use to reduce intraocular pressure in glaucoma.

3-Quinclidinol dl-form acetate hydrochloride Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 116mg/kg (116mg/kg) AUTONOMIC NERVOUS SYSTEM: OTHER (DIRECT) PARASYMPATHOMIMETIC Arzneimittel-Forschung. Drug Research. Vol. 18, Pg. 322, 1968.
mouse LD50 intravenous 27mg/kg (27mg/kg) AUTONOMIC NERVOUS SYSTEM: OTHER (DIRECT) PARASYMPATHOMIMETIC Arzneimittel-Forschung. Drug Research. Vol. 18, Pg. 322, 1968.
mouse LD50 oral 165mg/kg (165mg/kg)   Farmakologiya i Toksikologiya Vol. 23, Pg. 398, 1960.
mouse LD50 subcutaneous 102mg/kg (102mg/kg)   Farmakologiya i Toksikologiya Vol. 23, Pg. 398, 1960.
rat LD50 intraperitoneal 105mg/kg (105mg/kg) AUTONOMIC NERVOUS SYSTEM: OTHER (DIRECT) PARASYMPATHOMIMETIC Arzneimittel-Forschung. Drug Research. Vol. 18, Pg. 322, 1968.
rat LD50 intravenous 45mg/kg (45mg/kg)   Farmakologiya i Toksikologiya Vol. 23, Pg. 398, 1960.
rat LD50 subcutaneous 225mg/kg (225mg/kg)   Farmakologiya i Toksikologiya Vol. 23, Pg. 398, 1960.

3-Quinclidinol dl-form acetate hydrochloride Safety Profile

Poison by intraperitoneal and intravenous routes. When 3-Quinclidinol dl-form acetate hydrochloride (CAS NO.6109-70-2) is heated to decomposition, it emits very toxic fumes of NOx and HCl. See also ESTERS.

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