4-(FMOC-HYDRAZINO)-BENZOIC ACID

The Hydrazinecarboxylicacid, 2-(4-carboxyphenyl)-, 1-(9H-fluoren-9-ylmethyl) ester, with the CAS registry number 214475-53-3, is also known as 4-(2-Fmoc-hydrazino)benzoic acid. It belongs to the product categories of Aromatic Amino Acids; Peptide Synthesis; Unnatural Amino Acid Derivatives. This chemical's molecular formula is C₂₂H₁₈N₂O₄ and molecular weight is 374.39. What's more, its systematic name is 4-{2-[(9H-fluoren-9-ylmethoxy)carbonyl]hydrazino}benzoic acid. Its storage temperature is 2 - 8°C.

Physical properties of Hydrazinecarboxylicacid, 2-(4-carboxyphenyl)-, 1-(9H-fluoren-9-ylmethyl) ester are: (1)ACD/LogP: 4.47 ; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 3.57; (4)ACD/LogD (pH 7.4): 1.87; (5)ACD/BCF (pH 5.5): 184.92; (6)ACD/BCF (pH 7.4): 3.66; (7)ACD/KOC (pH 5.5): 810.5; (8)ACD/KOC (pH 7.4): 16.03; (9)#H bond acceptors: 6; (10)#H bond donors: 3; (11)#Freely Rotating Bonds: 6; (12)Polar Surface Area: 59.08 Å²; (13)Index of Refraction: 1.687; (14)Molar Refractivity: 104.6 cm³; (15)Molar Volume: 274.5 cm³; (16)Polarizability: 41.46×10^-24cm³; (17)Surface Tension: 65 dyne/cm; (18)Density: 1.363 g/cm³.

Preparation of Hydrazinecarboxylicacid, 2-(4-carboxyphenyl)-, 1-(9H-fluoren-9-ylmethyl) ester: this chemical can be prepared by 4-hydrazino-benzoic acid and 9H-fluoren-9-ylmethyl chloroformate. This reaction will need reagent aq. sodium bicarbonate and solvent dioxane. The yield is about 75%.

When you are using this chemical, please be cautious about it as the following:
It is irritating to eyes, respiratory system and skin. In case of contact with eyes, you should rinse immediately with plenty of water and seek medical advice. When using it, you need wear suitable protective clothing.

You can still convert the following datas into molecular structure:
(1)SMILES: O=C(O)c1ccc(cc1)NNC(=O)OCC4c2ccccc2c3c4cccc3
(2)Std. InChI: InChI=1S/C22H18N2O4/c25-21(26)14-9-11-15(12-10-14)23-24-22(27)28-13-20-18-7-3-1-5-16(18)17-6-2-4-8-19(17)20/h1-12,20,23H,13H2,(H,24,27)(H,25,26)
(3)Std. InChIKey: MLVJMSRGLQCZDE-UHFFFAOYSA-N