4-Fluorophenethyl alcohol

The CAS registry number of Benzeneethanol,4-fluoro- is 7589-27-7. Its EINECS registry number is 231-499-5. In addition, the molecular formula is C₈H₉FO and the molecular weight is 140.16. The systematic name is 2-(4-fluorophenyl)ethanol. What's more, it is a kind of colorless to light yellow liquid and can be used as a pharmaceutical intermediate. Besides, it should be stored in sealed container, and put in a cool and dry place.

Physical properties about this chemical are: (1)ACD/LogP: 1.41; (2)ACD/LogD (pH 5.5): 1.41; (3)ACD/LogD (pH 7.4): 1.41; (4)ACD/BCF (pH 5.5): 6.95; (5)ACD/BCF (pH 7.4): 6.95; (6)ACD/KOC (pH 5.5): 139.46; (7)ACD/KOC (pH 7.4): 139.46; (8)#H bond acceptors: 1; (9)#H bond donors: 1; (10)#Freely Rotating Bonds: 3; (11)Polar Surface Area: 9.23 Å²; (12)Index of Refraction: 1.514; (13)Molar Refractivity: 37.33 cm³; (14)Molar Volume: 123.9 cm³; (15)Polarizability: 14.79 ×10^-24cm³; (16)Surface Tension: 37.9 dyne/cm; (17)Density: 1.13 g/cm³; (18)Flash Point: 102.2 °C; (19)Enthalpy of Vaporization: 47.49 kJ/mol; (20)Boiling Point: 213 °C at 760 mmHg; (21)Vapour Pressure: 0.0994 mmHg at 25°C.

Preparation of Benzeneethanol,4-fluoro-: it can be prepared by (4-fluoro-phenyl)-acetic acid. This reaction will need reagent BH₃*THF and solvent tetrahydrofuran. The yield is about 90% by heating.

Uses of Benzeneethanol,4-fluoro-: it can be used to get 1-(2-bromo-ethyl)-4-fluoro-benzene. This reaction will need reagent PBr₃ and solvent diethyl ether. The yield is about 61% at reaction temperature of 0 °C.

When you are using this chemical, please be cautious about it as the following:
This chemical is harmful by inhalation, in contact with skin. And it is irritating to eyes, respiratory system and skin. Moreover, it can cause burns. During using it, wear suitable protective clothing, gloves and eye/face protection. You can not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer). And you should avoid contact with skin and eyes. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. In addition, in case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.). Besides, you should take off immediately all contaminated clothing.

You can still convert the following datas into molecular structure:
(1)SMILES: Fc1ccc(cc1)CCO
(2)Std.InChI: InChI=1S/C8H9FO/c9-8-3-1-7(2-4-8)5-6-10/h1-4,10H,5-6H2
(3)Std.InChIKey: MWUVGXCUHWKQJE-UHFFFAOYSA-N