Product Name

Stability

    Stable. Store cool. Incompatible with strong oxidizing agents.

Toxicology

    Harmful if inhaled, swallowed or absorbed through the skin.Possible risk of harm to the unborn child.

    x.

  • Risk Codes R20/21/22;R63   
  • Molecular Structure Molecular Structure of 68047-06-3 (4-HYDROXYTAMOXIFEN)
  • Hazard Symbols
  • Synonyms Phenol,4-[(1Z)-1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenyl-1-butenyl]- (9CI); Phenol,4-[1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenyl-1-butenyl]-, (Z)-;(Z)-4-Hydroxytamoxifen; 4-Hydroxy-(Z)-tamoxifen; 4-Hydroxytamoxifen;4-[(1Z)-1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenyl-1-butenyl]phenol;Hydroxytamoxifen; ICI 79280; trans-4-Hydroxytamoxifen; trans-Hydroxytamoxifen
  • PSA 32.70000
  • LogP 5.70170

4-Hydroxytamoxifen Chemical Properties

IUPAC Name:  4-[(Z)-1-[4-(2-dimethylaminoethyloxy)phenyl]-2-phenylbut-1-enyl]phenol
Synonyms:  4-{(1Z)-1-[{4-[2-(dimethylamino)ethoxy]phenyl}(phenyl)methylidene]propyl}phenol ; 4-Hydroxytamoxifen ; 4-hydroxy-tamoxifen ; 4-{1-[1-[4-(2-Dimethylamino-ethoxy)-phenyl]-1-phenyl-meth-(Z)-ylidene]-propyl}-phenol ; 4-{2-[4-(2-dimethylaminoethoxy)phenyl]-1-ethyl-2-phenylvinyl}phenol ; 4'-Hydroxy Tamoxifen
The Molecular Formula of  4-Hydroxytamoxifen (CAS NO.68047-06-3):C26H29NO2
The Molecular Weight of  4-Hydroxytamoxifen (CAS NO.68047-06-3):387.514 g/mol
The Molecular Structure of  4-Hydroxytamoxifen (CAS NO.68047-06-3):
Index of Refraction: 1.596
Molar Refractivity: 120.77 cm3
Molar Volume: 354.6 cm3
Surface Tension: 43.9 dyne/cm
Density: 1.092 g/cm3
Flash Point: 264.9 °C
Enthalpy of Vaporization: 81.57 kJ/mol
Boiling Point: 514.4 °C at 760 mmHg
Vapour Pressure: 3.35E-11 mmHg at 25°C

4-Hydroxytamoxifen Uses

  4-Hydroxytamoxifen ,whose cas register No. is 68047-06-3,can be used as pharmaceutical intermediate.

4-Hydroxytamoxifen Toxicity Data With Reference

1.    

mnt-hmn-lym 125 µg/L

    CRNGDP    Carcinogenesis. 18 (1997),303.
2.    

sln-hmn-lym 250 µg/L

    CRNGDP    Carcinogenesis. 18 (1997),303.

4-Hydroxytamoxifen Safety Profile

 Human mutation data reported. When heated to decomposition it emits toxic vapors of NOx.
Hazard Codes: HarmfulXn
Risk Statements: 20/21/22-63
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed. Experimental reproductive effects.
R63:Possible risk of harm to the unborn child.
Safety Statements: 22-23-36 
S22:Do not breathe dust. 
S23:Do not breathe vapour. 
S36:Wear suitable protective clothing.
WGK Germany: 3
RTECS: SL1210000