Product Name

  • Name

    4-Methylumbelliferone

  • EINECS 201-986-7
  • CAS No. 90-33-5
  • Article Data217
  • CAS DataBase
  • Density 1.319 g/cm3
  • Solubility slightly soluble in water
  • Melting Point 188.5-190 °C(lit.)
  • Formula C10H8O3
  • Boiling Point 377.4 °C at 760 mmHg
  • Molecular Weight 176.18
  • Flash Point 174.5 °C
  • Transport Information
  • Appearance off-white to yellow crystals
  • Safety 26-37/39-36
  • Risk Codes 36/37/38-20/21/22
  • Molecular Structure Molecular Structure of 90-33-5 (4-Methylumbelliferone)
  • Hazard Symbols IrritantXi,HarmfulXn
  • Synonyms Coumarin,7-hydroxy-4-methyl- (8CI);Umbelliferone, 4-methyl- (6CI);4-MU;4-Methyl-7-hydroxycoumarin;7-Hydroxy-4-methyl-2-chromenone;7-Hydroxy-4-methyl-2-oxo-3-chromene;7-Hydroxy-4-methyl-2H-1-benzopyran-2-one;7-Hydroxy-4-methyl-2H-chromen-2-one;7-Hydroxy-4-methylcoumarin;Bilcolic;Bilicante;Biliton H;Cantabilin;Cantabiline;Cholestil;Cholonerton;Cholspasmin;Coumarin 4;Cumarote C;Eurogale;Hymecromone;Imecromone;Medilla;Mendiaxon;NSC 9408;Omega127;Pilot 447;
  • PSA 50.44000
  • LogP 1.80700

4-Methylumbelliferone Chemical Properties

7-Hydroxy-4-methylcoumarin(90-33-5), also called 4-Methylumbelliferone, exists as off-white to yellow crystals. 7-Hydroxy-4-methylcoumarin(90-33-5) is slightly soluble in water.
Molecular Structure:
Molecular Formula: C10H8O3.
Molecular Weight: 176.17.
Melting Point: 188.5-190 ℃(lit.)

4-Methylumbelliferone Uses

7-Hydroxy-4-methylcoumarin(90-33-5) is mainly used as pharmaceutical intermediates. 7-Hydroxy-4-methylcoumarin(90-33-5) is a cholagogue and  the intermediate of sodium cromoglicate that is a antiallergic agent.

4-Methylumbelliferone Toxicity Data With Reference

1.rat LD50 oral > 3.85gm/kg (3850mg/kg) 
National Technical Information Service. Vol. OTS0533525

4-Methylumbelliferone Safety Profile

Irritating to eyes, respiratory system and skin. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Hazard Codes: Xi,Xn
Risk Statements: 36/37/38-20/21/22
36/37/38:  Irritating to eyes, respiratory system and skin
20/21/22:  Harmful by inhalation, in contact with skin and if swallowed 
Safety Statements: 26-37/39-36
26:  In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 
37/39:  Wear suitable gloves and eye/face protection 
36:  Wear suitable protective clothing 
WGK Germany: 2
RTECS: GN7000000
Hazard Note: Irritant
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