5-AMINOINDAZOLE

The IUPAC name of 5-Indazolamine is 5-Indazolamine. With the CAS registry number 19335-11-6, it is also named as 5-Aminoindazole. The product's categories are Amines and Anilines; Heterocycles; Pharmacetical; Indazole; Building Blocks; Heterocyclic Building Blocks; Indazoles. Besides, it is white to light yellow crystal powder, which should be stored in a closed, dark, ventilated, dry place. In addition, its molecular formula is C₇H₇N₃ and molecular weight is 133.15.

The other characteristics of 5-Indazolamine can be summarized as: (1)EINECS: 242-971-5; (2)ACD/LogP: 0.73; (3)# of Rule of 5 Violations: 0; (4)ACD/LogD (pH 5.5): 0.722; (5)ACD/LogD (pH 7.4): 0.729; (6)ACD/BCF (pH 5.5): 2.072; (7)ACD/BCF (pH 7.4): 2.11; (8)ACD/KOC (pH 5.5): 58.336; (9)ACD/KOC (pH 7.4): 59.382; (10)#H bond acceptors: 3; (11)#H bond donors: 3; (12)#Freely Rotating Bonds: 1; (13)Index of Refraction: 1.78; (14)Molar Refractivity: 40.856 cm³; (15)Molar Volume: 97.376 cm³; (16)Surface Tension: 79.421 dyne/cm; (17)Density: 1.367 g/cm³; (18)Flash Point: 209.521 °C; (19)Melting Point: 175-178 °C; (20)Water Solubility: 2.49E+04 mg/L at 25 °C; (21)Enthalpy of Vaporization: 62.427 kJ/mol; (22)Boiling Point: 376.609 °C at 760 mmHg; (23)Vapour Pressure: 0 mmHg at 25 °C.

Uses of 5-Indazolamine: it can react with Trichloroacetaldehyde hydrate to get 2-Hydroxyimino-N-(1H-indazol-5-yl)-acetamide.



This reaction needs conc. HCl, Hydroxylammoniumchloride, Na₂SO₄^.10 H₂O and H₂O by heating for 2 min. The yield is 89 %.

When you are using this chemical, please be cautious about it as the following: it is irritating to eyes, respiratory system and skin. It is also toxic if swallowed. In case of contact with eyes, please rinse immediately with plenty of water and seek medical advice. And you should wear suitable protective clothing, gloves and eye/face protection. Moreover, in case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)

People can use the following data to convert to the molecule structure.
(1)SMILES: c1cc2cn[nH]c2cc1N
(2)InChI: InChI=1/C7H7N3/c8-6-2-1-5-4-9-10-7(5)3-6/h1-4H,8H2,(H,9,10)
(3)InChIKey: KEJFADGISRFLFO-UHFFFAOYAE
(4)Std. InChI: InChI=1S/C7H7N3/c8-6-2-1-5-4-9-10-7(5)3-6/h1-4H,8H2,(H,9,10)
(5)Std. InChIKey: KEJFADGISRFLFO-UHFFFAOYSA-N

The toxicity data is as follows: