6-Aminoindazole

The 6-Aminoindazole, with the CAS registry number 6967-12-0, is also known as Indazol-6-ylamine. It belongs to the product categories of Amines and Anilines; Heterocycles; Pharmacetical; Indazoles; Building Blocks; Heterocyclic Building Blocks. Its EINECS registry number is 230-177-1. This chemical's molecular formula is C₇H₇N₃ and molecular weight is 133.15058. Its IUPAC name is called 1H-indazol-6-amine. What's more, this chemical's classification code is Drug / Therapeutic Agent.

Physical properties of 6-Aminoindazole: (1)ACD/LogP: 0.73; (2)ACD/LogD (pH 5.5): 0.722; (3)ACD/LogD (pH 7.4): 0.729; (4)ACD/BCF (pH 5.5): 2.072; (5)ACD/BCF (pH 7.4): 2.11; (6)ACD/KOC (pH 5.5): 58.336; (7)ACD/KOC (pH 7.4): 59.382; (8)#H bond acceptors: 3; (9)#H bond donors: 3; (10)#Freely Rotating Bonds: 1; (11)Index of Refraction: 1.78; (12)Molar Refractivity: 40.856 cm³; (13)Molar Volume: 97.376 cm³; (14)Surface Tension: 79.421 dyne/cm; (15)Density: 1.367 g/cm³; (16)Flash Point: 209.521 °C; (17)Enthalpy of Vaporization: 62.427 kJ/mol; (18)Boiling Point: 376.609 °C at 760 mmHg; (19)Vapour Pressure: 0 mmHg at 25°C.

Uses of 6-Aminoindazole: it can be used to produce ethylidene-(1H-indazol-6-yl)-amine with acetaldehyde at ambient temperature. This reaction will need solvent methanol with reaction time of 1.5 hours. The yield is about 92%.

When you are using this chemical, please be cautious about it as the following:
This chemical may cause damage to health. It is irritating to eyes, respiratory system and skin. In case of contact with eyes, you should rinse immediately with plenty of water and seek medical advice.

You can still convert the following datas into molecular structure:
(1)Canonical SMILES: C1=CC2=C(C=C1N)NN=C2
(2)InChI: InChI=1S/C7H7N3/c8-6-2-1-5-4-9-10-7(5)3-6/h1-4H,8H2,(H,9,10)
(3)InChIKey: KEJFADGISRFLFO-UHFFFAOYSA-N

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	oral	2gm/kg (2000mg/kg)		Chimica Therapeutica. Vol. 5, Pg. 24, 1970.