Product Name: 7-Hydroxymethotrexate (CAS NO.5939-37-7)
Molecular Formula: C20H22N8O6
Molecular Weight: 470.44g/mol
Mol File: 5939-37-7.mol
Appearance: Yellow Solid
Melting Point: 230°C dec.
Storage Temperature: −20°C
Density: 1.68 g/cm3
Surface Tension: 80.1 dyne/cm
XLogP3-AA: -0.8
H-Bond Donor: 6
H-Bond Acceptor: 12
Product Categories: Various Metabolites and Impurities; Intermediates and Fine Chemicals; Metabolites; Pharmaceuticals
A metabolite of Methotrexate, which is used as a antineoplastic and antirheumatic.
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
rat | LD50 | intravenous | 300mg/kg (300mg/kg) | Cancer Chemotherapy and Pharmacology. Vol. 37, Pg. 415, 1996. |
A poison by intravenous route. When heated to decomposition it emits toxic vapors of NOx.
7-Hydroxymethotrexate ,its CAS NO. is 5939-37-7,the synonyms is 7-Hydroxy methotrexate ; 7-Hydroxy methoxtrexate;glutamicacid,n-(p-(((2,4-diamino-7-hydroxy-6-pteridinyl)methyl)methylamino) ; l-Glutamicacid,n-(4-(((2,4-diamino-1,7-dihydro-7-oxo-6-pteridinyl)methyl)meth ; Ylamino)benzoyl)- ; l-(+)-7-Hydroxyamethopterin ; 7-Hydroxy amethopterin, 4-amino-7-hydroxy-10-methylpteroylglutamic acid ; 7-OH-mtx .
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View