Product Name

  • Name

    7-Hydroxy-5-methyl-1,3,4-triazaindolizine

  • EINECS 219-706-7
  • CAS No. 2503-56-2
  • Article Data17
  • CAS DataBase
  • Density 1.609 g/cm3
  • Solubility insoluble in cold water
  • Melting Point 280-283 °C(lit.)
  • Formula C6H6N4O
  • Boiling Point 271.66°C (rough estimate)
  • Molecular Weight 150.14
  • Flash Point
  • Transport Information
  • Appearance white fine crystalline powder
  • Safety 26-36-37/39
  • Risk Codes 36/37/38
  • Molecular Structure Molecular Structure of 2503-56-2 (7-Hydroxy-5-methyl-1,3,4-triazaindolizine)
  • Hazard Symbols IrritantXi
  • Synonyms s-Triazolo[1,5-a]pyrimidin-7-ol,5-methyl- (6CI,7CI,8CI);1,3,7-Triaza-4-hydroxy-6-methylindolizine;4-Hydroxy-6-methyl-1,2,4-triazolo[2,3-a]pyrimidine;4-Hydroxy-6-methyl-1,3,3a,7-tetraazaindene;5-Methyl-7-hydroxy-1,2,4-triazolo[1,5-a]pyrimidine;5-Methyl-7-hydroxy-1,3,4-triazaindolizine;5-Methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-ol;5-Methyl-s-triazolo[1,5-a]pyrimidin-7-ol;6-Methyl-4-hydroxy-1,3,3a,7-tetraazaindene;7-Hydroxy-5-methyl-s-triazolo[1,5-a]pyrimidine;NSC 32071;TAI;TAI (sensitizer);
  • PSA 63.31000
  • LogP 0.13830

7-Hydroxy-5-methyl-1,3,4-triazaindolizine Chemical Properties

Molecular Formula:C6H6N4O        
Molar mass:150.138g/mol
Structure :
        
Synonyms :5-Methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-ol;5-Methyl-7-hydroxy-1,2,4-triazolo[1,5-a]pyrimidine;[1,2,4]Triazolo[1,5-a]pyrimidin-7-ol, 5-methyl-;5-Methyl-s-triazolo[1,5-a]pyrimidin-7-ol
Density:1.6 g/cm3                             
Index of Refraction:1.772                            
Melting point:280-283°C   
Water solubility:INSOLUBLE IN COLD WATER

7-Hydroxy-5-methyl-1,3,4-triazaindolizine Uses

7-Hydroxy-5-methyl-1,3,4-triazaindolizine(2503-56-2) can be used as intermediates of durg: yl-ethyl amine.
7-Hydroxy-5-methyl-1,3,4-triazaindolizine(2503-56-2) also can be used as a film of anti-fog agent.

7-Hydroxy-5-methyl-1,3,4-triazaindolizine Production

3 - amino-1,2,4 - triazole with ethyl acetoacetate, in glacial acetic acid, was refluxed 4 hours, then has the reaction of the cyclization to derive the product.

7-Hydroxy-5-methyl-1,3,4-triazaindolizine Toxicity Data With Reference

1.mouse LD50 intravenous > 450mg/kg (450mg/kg)  
Oyo Yakuri. Pharmacometrics. Vol. 13, Pg. 597, 1977.
2. Carcinogenicity of 7-Hydroxy-5-methyl-1,3,4-triazaindolizine(2503-56-2) hasn't been listed as a carcinogen by  NTP, IARC,ACGIH, or CA Prop 65.You can see actual entry in RTECS for complete information.

7-Hydroxy-5-methyl-1,3,4-triazaindolizine Safety Profile

Hazard Codes:Xi
Risk Statements:
36:  Irritating to the eyes
37:  Irritating to the respiratory system
38:  Irritating to the skin
Safety Statements:
26:  In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36:  Wear suitable protective clothing 
37:  Wear suitable gloves
39:  Wear eye/face protection

7-Hydroxy-5-methyl-1,3,4-triazaindolizine Specification

Polymerization of the 7-Hydroxy-5-methyl-1,3,4-triazaindolizine(2503-56-2) is stable under normal temperature and pressure conditions, and you must not take it with strong oxidants.And also prevent it to broken down into hazardous decomposition products:irritating and toxic fumes and gases.and its polymerization is hazardous.
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