Achromycin supplier | CasNO.53-79-2

Name
PUROMYCIN
EINECS
CAS No. 53-79-2
Article Data10
CAS DataBase
Density 1.51 g/cm³
Solubility Soluble in water (50 mg/ml at 20°C).
Melting Point 175.5-177°
Formula C22H29 N7 O5
Boiling Point °Cat760mmHg
Molecular Weight 471.516
Flash Point °C
Transport Information
Appearance
Safety Poison by ingestion, intravenous, and intraperitoneal routes. An experimental teratogen. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of NO_x. An antibiotic.
Risk Codes
Molecular Structure
Hazard Symbols Toxic to living cells of all kinds.
Synonyms Adenosine,3'-(a-amino-p-methoxyhydrocinnamamido)-3'-deoxy-N,N-dimethyl-,L- (8CI); Adenosine,3'-[[2-amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-deoxy-N,N-dimethyl-,(S)-; 1-MM; 3123L; 3'-(a-Amino-p-methoxyhydrocinnamamido)-3'-deoxy-N,N-dimethyladenosine;6-Dimethylamino-9-[3-deoxy-3-(p-methoxy-L-phenylalanylamino)-b-D-ribofuranosyl]-b-purine; Achromycin; Achromycin(purine derivative); CL 13900; P 638; Puromycin; Stillomycin; Stylomycin; b-D-Ribofuranoside,6-(dimethylamino)-9H-purine-9 3-deoxy-3-[(4-methoxy-L-phenylalanyl)amino]-
PSA 160.88000
LogP 0.29750

Achromycin Chemical Properties

IUPAC Name: (2S)-2-amino-N-[(2S,3S,4R,5R)-5-[6-(dimethylamino)purin-9-yl]-4-hydroxy-2-(hydroxymethyl)oxolan-3-
yl]-3-(4-methoxyphenyl)propanamide
Molecular Weight: 471.50956 g/mol
Molecular Formula: C₂₂H₂₉N₇O₅
Density: 1.51 g/cm³
Molar Volume: 311.7 cm³
Polarizability: 47.79*10^-24cm³
Surface Tension: 61.1 dyne/cm
H-Bond Donor: 4
H-Bond Acceptor: 10
Rotatable Bond Count: 8
Tautomer Count: 2
Exact Mass: 471.223017
MonoIsotopic Mass: 471.223017
Topological Polar Surface Area: 161
Heavy Atom Count: 34
Complexity: 680
Defined Atom StereoCenter Count: 5
Canonical SMILES: CN(C)C1=NC=NC2=C1N=CN2C3C(C(C(O3)CO)NC(=O)C(CC4=CC=C(C=C4)OC)N)O
Isomeric SMILES: CN(C)C1=NC=NC2=C1N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)CO)NC(=O)[C@H](CC4=CC=C(C=C4)OC)N)O
InChI: InChI=1S/C22H29N7O5/c1-28(2)19-17-20(25-10-24-19)29(11-26-17)22-18(31)16(15(9-30)34-22)27-21(32)14(23)8-12-4-6-13(33-3)7-5-12/h4-7,10-11,14-16,18,22,30-31H,8-9,23H2,1-3H3,(H,27,32)/t14-,15+,16+,18+,22+/m0/s1
InChIKey: RXWNCPJZOCPEPQ-NVWDDTSBSA-N

Achromycin Toxicity Data With Reference

1.	dnr-esc 100 µg/disc	CNREA8 Cancer Research. 34 (1974),1658.
2.	cyt-dmg:oth 100 mg/L	CLDFAT Cell Differentiation. 2 (1973),97.
3.	dni-oin:oth 100 mg/L	IJEBA6 Indian Journal of Experimental Biology. 16 (1978),1027.
4.	dni-mus:lym 100 µmol/L	PLMEAA Planta Medica. 34 (1978),231.
5.	dni-mus:fbr 420 µmol/L	JCLBA3 Journal of Cell Biology. 58 (1973),410.
6.	orl-mus LD50:20 mg/kg	85GDA2 CRC Handbook of Antibiotic Compounds. 5 (1981),302.
7.	ipr-mus LD50:25 mg/kg	85GDA2 CRC Handbook of Antibiotic Compounds. 5 (1981),302.
8.	ivn-mus LD50:15 mg/kg	85GDA2 CRC Handbook of Antibiotic Compounds. 5 (1981),302.

Achromycin Safety Profile

Poison by ingestion, intravenous, and intraperitoneal routes. An experimental teratogen. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of NO_x. An antibiotic.
RIDADR: 3249
HazardClass: 6.1(b)
PackingGroup: III

Achromycin Specification

Achromycin (CAS NO.53-79-2) is also called (s)-3'-((2-Amino-3-(4-methoxyphenyl)-1-oxopropyl)amino)-3'-deoxy-n,n-dimethy;1-mm ; 3'-(Alpha-amino-p-methoxyhydrocinnamamido)-3'-deoxy-n,n-dimethyl-adenosinl ; 3'-(l-Alpha-amino-p-methoxyhydrocinnamamido)-3'-deoxy-n,n-dimethyladenosine ; 6-Dimethylamino-9-(3'-(p-methoxy-l-phenylalanylamino)-beta-d-ribofuranosyl)- ; ; Achromycin(purinederivative) . Achromycin (CAS NO.53-79-2) is high toxic. It is flammable by fire. It will produce toxic nitrogen oxide fumes when buring. So the storage environment should be ventilate, low-temperature and dry. Keep Achromycin (CAS NO.53-79-2) separate from oxidants and food additives .

Product Name

PUROMYCIN

Achromycin Chemical Properties

Achromycin Toxicity Data With Reference

Achromycin Safety Profile

Achromycin Specification

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