Formaldehyde was first reported by the Russian chemist Aleksandr Butlerov (1828-1886), but it was conclusively identified by August Wilhelm von Hofmann.
Molecular Structure of Alclofenac epoxide (CAS NO.70319-10-7):
IUPAC: [3-Chloro-4-(oxiran-2-ylmethoxy)phenyl]acetic acid
Molecular Formula: C11H11ClO4
Molecular Weight: 242.6556
Density: 1.401 g/cm3
Boiling point: 411.2oC at 760 mmHg
Flash point: 202.5oC
Index of Refraction: 1.581
Surface Tension: 56.7 dyne/cm
Enthalpy of Vaporization: 69.97 kJ/mol
Vapour Pressure: 1.69E-07 mmHg at 25oC
mmo-sat 100 µg/plate
|JJATDK JAT, Journal of Applied Toxicology. 3 (1983),230.|
otr-ham:emb 125 mg/L
|CBINA8 Chemico-Biological Interactions. 34 (1981),95.|
Mutation data reported. When heated to decomposition it emits toxic fumes of Cl−.
Alclofenac epoxide with cas registry number of 70319-10-7 is also known as (3-beta,5-alpha,15-beta)-19-Oxo-3,14,15-trihydroxycard-20(22)-enolide ; Alloglaucotoxigenin ; Alloglucotoxigenin ; 5-alpha-Card-20(22)-enolide, 3-beta,14,15-beta-trihydroxy-19-oxo- (8CI) ; Card-20(22)-enolide, 19-oxo-3,14,15-trihydroxy-, (3-beta,5-alpha,15-beta)- . Alclofenac epoxide was shown to inhibit the activity of yeast alcohol dehydrogenase and form a conjugate with cysteine. It showed mutagenic effects on strains of Salmonella typhimurium sensitive to alkylating agents, but had no effect on strains sensitive to intercalating agents. Alclofenac epoxide with cas registry number of 70319-10-7 is used as a intermediate.