Product Name

  • Name

    AMPHOTERICIN B, METHYL ESTER HYDROCHLORIDE

  • EINECS
  • CAS No. 35375-29-2
  • Density
  • Solubility
  • Melting Point
  • Formula C47H75NO20•ClH
  • Boiling Point
  • Molecular Weight 1010.69
  • Flash Point
  • Transport Information
  • Appearance
  • Safety Poison by intravenous route. See also ESTERS. Moderately toxic by intraperitoneal route. When heated to decomposition it emits very toxic fumes of NOx and HCl.
  • Risk Codes
  • Molecular Structure Molecular Structure of 35375-29-2 (AMPHOTERICIN B, METHYL ESTER HYDROCHLORIDE )
  • Hazard Symbols 3
  • Synonyms
  • PSA
  • LogP

Amphotericin b, methyl ester hydrochloride Chemical Properties

Molecular Structure of Amphotericin b, methyl ester hydrochloride (CAS NO. 35375-29-2):

IUPAC Name: methyl (1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19E,21E,23E,25E,27E,29E,31E,33R,35S,36R,37S)-
33-[(2R,3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylate hydrochloride 
Empirical Formula: C48H76ClNO17 
Molecular Weight: 974.5665
Flash Point: 620.6 °C 
Enthalpy of Vaporization: 183.21 kJ/mol 
Boiling Point: 1102.6 °C at 760 mmHg 
Vapour Pressure: 0 mmHg at 25°C 

Amphotericin b, methyl ester hydrochloride Toxicity Data With Reference

1.    

ipr-mus LD50:1320 mg/kg

     SCIEAS    Science. 179 (1973),584.
2.    

ivn-mus LD50:75 mg/kg

     85ERAY    Antibiotics: Origin, Nature, and Properties. 2 (1978),1019.
3.    

ivn-dog LD50:48 mg/kg

     SCIEAS    Science. 179 (1973),584.

Amphotericin b, methyl ester hydrochloride Safety Profile

Poison by intravenous route. See also ESTERS. Moderately toxic by intraperitoneal route. When heated to decomposition it emits very toxic fumes of NOx and HCl.

Amphotericin b, methyl ester hydrochloride Specification

 Amphotericin b, methyl ester hydrochloride ,its CAS number is 35375-29-2,it can be called AME hydrochloride and Amphotericin B .

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