Product Name

  • Name

    Bevantolol hydrochloride

  • EINECS
  • CAS No. 42864-78-8
  • Article Data2
  • CAS DataBase
  • Density
  • Solubility
  • Melting Point 137-138°
  • Formula C20H27NO4.HCl
  • Boiling Point 518.3 °C at 760 mmHg
  • Molecular Weight 381.9
  • Flash Point 267.3 °C
  • Transport Information
  • Appearance
  • Safety
  • Risk Codes
  • Molecular Structure Molecular Structure of 42864-78-8 (Bevantolol hydrochloride)
  • Hazard Symbols
  • Synonyms 2-Propanol,1-[[2-(3,4-dimethoxyphenyl)ethyl]amino]-3-(3-methylphenoxy)-, hydrochloride(9CI);1-[(3,4-Dimethoxyphenethyl)amino]-3-(m-tolyloxy)-2-propanolhydrochloride;Bevantolol hydrochloride;CI 775;Cl 775;NC 1400;Ranestol;Sentiloc;Vantol;1-{[2-(3,4-dimethoxyphenyl)ethyl]amino}-3-(3-methylphenoxy)propan-2-ol hydrochloride (1:1);
  • PSA 59.95000
  • LogP 3.77710

BEVANTOLOL HYDROCHLORIDE Chemical Properties

Molecular Structure of BEVANTOLOL HYDROCHLORIDE (42864-78-8):

IUPAC Name: 1-[2-(3,4-dimethoxyphenyl)ethylamino]-3-(3-methylphenoxy)propan-2-ol hydrochloride
Molecular Formula:C20H28ClNO4
Molecular Weight:381.893620 g/mol
Flash Point:267.3 °C
Enthalpy of Vaporization:83.26 kJ/mol
Boiling Point:518.3 °C at 760 mmHg
Vapour Pressure:1.44E-11 mmHg at 25 °C
Synonyms of BEVANTOLOL HYDROCHLORIDE (42864-78-8):
 2-PROPANOL, 1-[[2-(3,4-DIMETHOXYPHENYL)ETHYL]AMINO]-3-(3-METHYLPHENOXY)-, HYDROCHLORIDE ; 1-((2-(3,4-dimethoxyphenyl)ethyl)amino)-3-(3-methylphenoxy)-2-propanol hydrochloride ; BEVANTOLOL HCL ; bevantolol hydrochloride ; BEVANTOLOLHYDROCHLORIDE(FORR&DONLY) ; 1-[(3,4-Dimethoxyphenethyl)amino]-3-(m-tolyloxy)-2-propanol hydrochloride ; CI 775 ; Cl 775

BEVANTOLOL HYDROCHLORIDE Uses

 BEVANTOLOL HYDROCHLORIDE (42864-78-8) is used for the treatment of mild or moderate hypertension and angina pectoris.

BEVANTOLOL HYDROCHLORIDE Toxicity Data With Reference

1.   

orl-rat LD50:460 mg/kg

   IYKEDH    Iyakuhin Kenkyu. Study of Medical Supplies. 26 (1995),364.
2.   

ipr-rat LD50:130 mg/kg

   IYKEDH    Iyakuhin Kenkyu. Study of Medical Supplies. 26 (1995),364.
3.   

ivn-rat LD50:25,100 µg/kg

   IYKEDH    Iyakuhin Kenkyu. Study of Medical Supplies. 26 (1995),364.
4.   

orl-mus LD50:419 mg/kg

   NCDREP    New Cardiovascular Drugs. 3 (1985),85.
5.   

orl-dog LD50:436 mg/kg

   YAKUD5    Gekkan Yakuji. Pharmaceuticals Monthly. 37 (1995),1835.

BEVANTOLOL HYDROCHLORIDE Safety Profile

A poison by intraperitoneal and intravenous route. Moderately toxic by ingestion. When heated to decomposition it emits toxic vapors of NOx, HCl, and Cl−.

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