Product Name

  • Name

    capreomycin IA

  • EINECS
  • CAS No. 37280-35-6
  • Density 1.75g/cm3
  • Solubility
  • Melting Point 246-248° (dec)
  • Formula C25H44 N14 O8
  • Boiling Point °Cat760mmHg
  • Molecular Weight 668.83
  • Flash Point °C
  • Transport Information
  • Appearance
  • Safety Poison by intravenous route. Moderately toxic by subcutaneous route. When heated to decomposition it emits toxic fumes of NOx.
  • Risk Codes
  • Molecular Structure Molecular Structure of 37280-35-6 (capreomycin IA)
  • Hazard Symbols
  • Synonyms CapreomycinIA;Cyclo[3-[[(3S)-3,6-diamino-1-oxohexyl]amino]-L-alanyl-(2Z)-3-[(aminocarbonyl)amino]-2,3-didehydroalanyl-(2S)-2-[(4R)-2-amino-1,4,5,6-tetrahydro-4-pyrimidinyl]glycyl-(2S)-2-amino-b-alanyl-L-seryl] (9CI);1,4,7,10,13-Pentaazacyclohexadecane, cyclic peptide deriv.
  • PSA 375.92000
  • LogP -2.04080

CAPREOMYCIN IA Chemical Properties

Details of CAPREOMYCIN IA (37280-35-6).
Molecular Formula:C25H44N14O8
Molecular Weight:668.83
Density:1.75g/cm3
Properties:Crystals. Mp: 246–248°C.
Synonyms:capreomycin IA;Cyclo[A2pr*-Ser-N3-[(3S)-3,6-diamino-1-oxohexyl]A2pr-2-[(Z)-aminocarbonylaminomethylene]Gly-2-[(4R)-2-iminohexahydropyrimidine-4-yl]Gly-]
Structure:

CAPREOMYCIN IA Toxicity Data With Reference

1.   

orl-mus LD50:10 g/kg

   85GDA2    CRC Handbook of Antibiotic Compounds. 4 (1)(1980),288.
2.   

scu-mus LD50:514 mg/kg

   85GDA2    CRC Handbook of Antibiotic Compounds. 4 (1)(1980),288.
3.   

ivn-mus LD50:250 mg/kg

   85GDA2    CRC Handbook of Antibiotic Compounds. 4 (1)(1980),288.

CAPREOMYCIN IA (37280-35-6) has the toxicity.
1.mouse   LD50   intravenous   250mg/kg (250mg/kg)    "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980Vol. 4(1), Pg. 288, 1980.
2.mouse   LD50   oral              10gm/kg (10000mg/kg)   "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980Vol. 4(1), Pg. 288, 1980.

3.mouse  LD50  subcutaneous  514mg/kg (514mg/kg)   "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980Vol. 4(1), Pg. 288, 1980.

CAPREOMYCIN IA Safety Profile

Poison by intravenous route. Moderately toxic by subcutaneous route. When heated to decomposition it emits toxic fumes of NOx.

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