Product Name

  • Name

    oxprenolol

  • EINECS
  • CAS No. 6452-71-7
  • Article Data34
  • CAS DataBase
  • Density 1.0479 (rough estimate)
  • Solubility
  • Melting Point 78-80°
  • Formula C15H23 N O3
  • Boiling Point 408.57°C (rough estimate)
  • Molecular Weight 265.353
  • Flash Point
  • Transport Information
  • Appearance
  • Safety Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. Human systemic effects by ingestion: decreased pulse rate and blood pressure, and unspecified changes in the cardiovascular and respiratory systems. When heated to decomposition it emits toxic fumes of NOx. See also ALLYL COMPOUNDS.
  • Risk Codes
  • Molecular Structure Molecular Structure of 6452-71-7 (oxprenolol)
  • Hazard Symbols
  • Synonyms 2-Propanol,1-[(1-methylethyl)amino]-3-[2-(2-propenyloxy)phenoxy]- (9CI); 2-Propanol, 1-[o-(allyloxy)phenoxy]-3-(isopropylamino)-(7CI,8CI); (?à)-Oxprenolol;1-(Isopropylamino)-2-hydroxy-3-[o-(allyloxy)phenoxy]propane;1-[o-(Allyloxy)phenoxy]-3-(isopropylamino)-2-propanol; Coretal; Oxprenolol;dl-Oxprenolol
  • PSA 50.72000
  • LogP 2.38000

CORETAL Chemical Properties

Product Name: Coretal (CAS NO.6452-71-7)


Molecular Formula: C15H23NO3
Molecular Weight: 265.34802g/mol
Mol File: 6452-71-7.mol
Einecs: 229-257-9
Boiling point: 403.3 °C at 760 mmHg
Storage Temperature:
Flash Point: 197.7 °C
Density: 1.039 g/cm3
Surface Tension: 36.5 dyne/cm
Enthalpy of Vaporization: 69.02 kJ/mol
Vapour Pressure: 3.15E-07 mmHg at 25°C
XLogP3: 2.1
H-Bond Donor: 2
H-Bond Acceptor: 4

CORETAL Uses

 Coretal (CAS NO.6452-71-7) is a cardiovascular system drugs.

CORETAL Toxicity Data With Reference

1.    

orl-hmn TDLo:50 mg/kg:CVS,PUL

     BMJOAE    British Medical Journal. 1 (1977),776.
2.    

orl-rat LD50:730 mg/kg

     ARZNAD    Arzneimittel-Forschung. Drug Research. 18 (1968),164.
3.    

scu-rat LD50:940 mg/kg

     ARZNAD    Arzneimittel-Forschung. Drug Research. 18 (1968),164.
4.    

ivn-rat LD50:33 mg/kg

     ARZNAD    Arzneimittel-Forschung. Drug Research. 18 (1968),164.
5.    

ipr-mus LD50:170 mg/kg

     PJPPAA    Polish Journal of Pharmacology and Pharmacy. 25 (1973),145.
6.    

scu-mus LD50:245 mg/kg

     ARZNAD    Arzneimittel-Forschung. Drug Research. 18 (1968),164.
7.    

ivn-mus LD50:20 mg/kg

     ARZNAD    Arzneimittel-Forschung. Drug Research. 27 (1977),1022.
8.    

orl-cat LD90:200 mg/kg

     ARZNAD    Arzneimittel-Forschung. Drug Research. 18 (1968),164.
9.    

ivn-rbt LD90:20 mg/kg

     ARZNAD    Arzneimittel-Forschung. Drug Research. 18 (1968),164.

CORETAL Safety Profile

Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. Human systemic effects by ingestion: decreased pulse rate and blood pressure, and unspecified changes in the cardiovascular and respiratory systems. When heated to decomposition it emits toxic fumes of NOx. See also ALLYL COMPOUNDS.

CORETAL Specification

 Coretal ,its CAS NO. is 6452-71-7,the synonyms is 1-(2-Allyloxyphenoxy)-3-isopropylaminopropan-2-ol ; 2-Propanol, 1-(1-methylethyl)amino-3-2-(2-propenyloxy)phenoxy- ; 1-(Isopropylamino)-2-hydroxy-3-[o-(allyloxy)phenoxy]propane ; 1-[o-(Allyloxy)phenoxy]-3-(isopropylamino)-2-propanol ; 2-Propanol, 1-[(1-methylethyl)amino]-3-[2-(2-propenyloxy)phenoxy]- (9CI);2-Propanol, 1-[o-(allyloxy)phenoxy]-3-(isopropylamino)- (7CI, 8CI) ; Coretal ; dl-Oxprenolol .

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