Camazepam supplier | CasNO.36104-80-0

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Name
camazepam
EINECS 252-866-6
CAS No. 36104-80-0
Density 1.29g/cm³
Solubility
Melting Point 173-174°
Formula C19H18 Cl N3 O3
Boiling Point 568.3°Cat760mmHg
Molecular Weight 371.823
Flash Point 297.5°C
Transport Information
Appearance
Safety Moderately toxic by ingestion and intraperitoneal routes. A tranquilizer. See also CARBAMATES and DIAZEPAM. When heated to decomposition it emits very toxic fumes of Cl⁻ and NO_x.
Risk Codes
Molecular Structure
Hazard Symbols
Synonyms Carbamicacid, dimethyl-, 7-chloro-2,3-dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-ylester (9CI); 1H-1,4-Benzodiazepine, carbamic acid deriv.; (?à)-Camazepam; Albego; Camazepam;Racemic camazepam; SB 5833; dl-Camazepam
PSA 62.21000
LogP 2.67870

Camazepam Chemical Properties

Molecule structure of Camazepam (CAS NO.36104-80-0) :

IUPAC Name: (7-chloro-1-methyl-2-oxo-5-phenyl-3H-1,4-benzodiazepin-3-yl)N,N-dimethylcarbamate
Molecular Weight: 371.81752 g/mol
Molecular Formula: C₁₉H₁₈ClN₃O₃
Density: 1.29 g/cm³
Melting Point 173.5 °C
Boiling Point: 568.3 °C at 760 mmHg
Flash Point: 297.5 °C
Appreance: white crystalline powder
Solubility: soluble in ethanol and water
Molar Volume: 286.8 cm³
Polarizability: 39.86*10^-24 cm³
Surface Tension: 46.2 dyne/cm
Enthalpy of Vaporization: 85.29 kJ/mol
Vapour Pressure: 6.22E-13 mmHg at 25°C
log P (octanol-water): 2.660 (none)
Atmospheric OH Rate Constant: 2.09E-11 cm3/molecule-sec at 25 °C
XLogP3: 2.8
H-Bond Acceptor: 4
Rotatable Bond Count: 3
Exact Mass: 371.103669
MonoIsotopic Mass: 371.103669
Topological Polar Surface Area: 62.2
Heavy Atom Count: 26
Complexity: 574
Canonical SMILES: CN1C2=C(C=C(C=C2)Cl)C(=NC(C1=O)OC(=O)N(C)C)C3=CC=CC=C3
InChI: InChI=1S/C19H18ClN3O3/c1-22(2)19(25)26-17-18(24)23(3)15-10-9-13(20)11-14(15)16(21-17)12-7-5-4-6-8-12/h4-11,17H,1-3H3
InChIKey: PXBVEXGRHZFEOF-UHFFFAOYSA-N
EINECS: 252-866-6

Camazepam Uses

Camazepam (CAS NO.36104-80-0) is used as antipsychotic and antidepressant drugs.

Camazepam Production

Camazepam (CAS NO.36104-80-0) is made by 7-chloro-5-phenyl-1-methyl-3-hydroxy-1,3- dihydro-2H-1, 4-benzodiazepine-2- one with phenyl chloroformate condensation, and dimethylamine derived replacement.

Camazepam Toxicity Data With Reference

1.		orl-mus LD50:970 mg/kg		DRFUD4 Drugs of the Future. 1 (1976),458.
2.		ipr-mus LD50:800 mg/kg		DRFUD4 Drugs of the Future. 1 (1976),458.

Camazepam Safety Profile

Moderately toxic by ingestion and intraperitoneal routes. A tranquilizer. See also CARBAMATES and DIAZEPAM. When heated to decomposition it emits very toxic fumes of Cl⁻ and NO_x.
RIDADR: 3249
HazardClass: 6.1(b)
PackingGroup: III

Camazepam Specification

Camazepam (CAS NO.36104-80-0) is also called Albego; B-5333; Dimethylcarbamic acid 7-chloro-2,3-dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl ester ; KTH-497; SB-5833. Camazepam (CAS NO.36104-80-0) is moderate toxic. It is flammable. It will decomposit toxic hydrogen chloride, nitrogen oxide gas when buring. So the storage environment should be ventilate, low-temperature and dry.

Product Name

camazepam