Carbinoxamine maleate supplier

Name
CARBINOXAMINE MALEATE SALT
EINECS 222-498-0
CAS No. 3505-38-2
Article Data1
CAS DataBase
Density
Solubility Completely soluble in water
Melting Point 117-119 °C
Formula C₁₆H₁₉ClN₂O^.C₄H₄O₄
Boiling Point 579.1 °C at 760 mmHg
Molecular Weight 406.866
Flash Point 304 °C
Transport Information UN 3249
Appearance Off-white solid
Safety 26-36/37/39-45
Risk Codes 25-36/37/38
Molecular Structure
Hazard Symbols T
Synonyms 2-[p-Chloro-α-[2-(dimethylamino)ethoxy]benzyl]pyridine bimaleate;Lergefin;N-[2-[(4-Chlorophenyl)(2-pyridinyl)methoxy]ethyl]-N,N-dimethylamine maleate salt;Clistin maleate;p-Carbinoxamine maleate;Pyridine, 2-[p-chloro-.alpha.-[2- (dimethylamino)ethoxy]benzyl]-, maleate (1:1);Clistin;Allergefon maleate;Prestwick_238;Clistine Maleate;Ethanamine, 2-[(4-chlorophenyl)-2-pyridinylmethoxy]-N,N-dimethyl-, (2Z)-2-butenedioate (1:1);Ciberon;Paracarbinoxamine maleate;but-2-enedioic acid; 2-[(4-chlorophenyl)-pyridin-2-yl-methoxy]-N,N-dimethyl-ethanamine;
PSA 99.96000
LogP 3.11440

Carbinoxamine maleate Consensus Reports

Reported in EPA TSCA Inventory.

Carbinoxamine maleate Specification

The Carbinoxamine maleate, with the CAS registry number 3505-38-2, is also known as Pyridine, 2-[p-chloro-α-[2-(dimethylamino)ethoxy]benzyl]-, maleate (1:1). It belongs to the product categories of Intermediates & Fine Chemicals; Pharmaceuticals; Alphabetic; CA - CG Forensic and Veterinary Standards; Drugs & Metabolites; Neat Compounds; Aromatics; Heterocycles. Its EINECS number is 222-498-0. This chemical's molecular formula is C₁₆H₁₉ClN₂O·C₄H₄O₄ and molecular weight is 406.86. What's more, its systematic name is but-2-enedioic acid; 2-[(4-chlorophenyl)-(2-pyridyl)methoxy]-N,N-dimethyl-ethanamine. Its classification codes are: (1)Antihistaminic; (2)Drug / Therapeutic Agent; (3)Human Data. It has been used as an analgesic and an anti-inflammatory compound.

Physical properties of Carbinoxamine maleate are: (1)ACD/LogP: 2.76; (2)# of Rule of 5 Violations: 0; (3)#H bond acceptors: 7; (4)#H bond donors: 2; (5)#Freely Rotating Bonds: 8; (6)Polar Surface Area: 99.96 Å²; (7)Flash Point: 304 °C; (8)Enthalpy of Vaporization: 91.15 kJ/mol; (9)Boiling Point: 579.1 °C at 760 mmHg; (10)Vapour Pressure: 2.98E-14 mmHg at 25°C.

When you are using this chemical, please be cautious about it as the following:
This chemical is toxic if swallowed. It is irritating to eyes, respiratory system and skin. In case of contact with eyes, you should rinse immediately with plenty of water and seek medical advice. When using it, you need wear suitable protective clothing, gloves and eye/face protection. In case of accident or if you feel unwell, you must seek medical advice immediately (show the label where possible).

You can still convert the following datas into molecular structure:
(1)SMILES: OC(=O)C=CC(O)=O.Clc1ccc(cc1)C(OCCN(C)C)c2ccccn2
(2)Std. InChI: InChI=1S/C16H19ClN2O.C4H4O4/c1-19(2)11-12-20-16(15-5-3-4-10-18-15)13-6-8-14(17)9-7-13;5-3(6)1-2-4(7)8/h3-10,16H,11-12H2,1-2H3;1-2H,(H,5,6)(H,7,8)
(3)Std. InChIKey: GVNWHCVWDRNXAZ-UHFFFAOYSA-N

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
child	TDLo	oral	1880ug/kg/4D- (1.88mg/kg)	BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS" BEHAVIORAL: EXCITEMENT	Journal of Toxicology, Clinical Toxicology. Vol. 25, Pg. 161, 1987.
dog	LDLo	intravenous	36mg/kg (36mg/kg)		Compilation of LD50 Values of New Drugs.
guinea pig	LD50	oral	411mg/kg (411mg/kg)		Compilation of LD50 Values of New Drugs.
guinea pig	LD50	subcutaneous	120mg/kg (120mg/kg)		Annales Pharmaceutiques Francaises. Vol. 20, Pg. 463, 1962.
mouse	LD50	intraperitoneal	150mg/kg (150mg/kg)		Toho Igakkai Zasshi. Journal of Medical Society of Toho University. Vol. 15, Pg. 367, 1968.
mouse	LD50	intravenous	32mg/kg (32mg/kg)		Compilation of LD50 Values of New Drugs.
mouse	LD50	oral	162mg/kg (162mg/kg)		Compilation of LD50 Values of New Drugs.
mouse	LD50	subcutaneous	350mg/kg (350mg/kg)		Toho Igakkai Zasshi. Journal of Medical Society of Toho University. Vol. 15, Pg. 367, 1968.

Product Name

CARBINOXAMINE MALEATE SALT

Carbinoxamine maleate Consensus Reports

Carbinoxamine maleate Specification

Related Products

Hot Products