Product Name

  • Name

    CARZINOPHILIN

  • EINECS
  • CAS No. 1403-29-8
  • Density 1.5g/cm3
  • Solubility
  • Melting Point 219.5°C (rough estimate)
  • Formula C31H33 N3 O11
  • Boiling Point 994.3°C at 760 mmHg
  • Molecular Weight 639.67
  • Flash Point 555.1°C
  • Transport Information
  • Appearance
  • Safety Deadly poison by intravenous route. Mutation data reported.
  • Risk Codes
  • Molecular Structure Molecular Structure of 1403-29-8 (CARZINOPHILIN)
  • Hazard Symbols
  • Synonyms 1-Naphthalenecarboxylicacid, 3-methoxy-5-methyl-,2-[[1-[3-(acetyloxy)-4-hydroxy-1-azabicyclo[3.1.0]hex-2-ylidene]-2-[[1-(hydroxymethylene)-2-oxopropyl]amino]-2-oxoethyl]amino]-1-(2-methyloxiranyl)-2-oxoethylester, [3R-[2E[1[S*(S*)],2(E)],3a,4b,5a]]-; 1-Azabicyclo[3.1.0]hexane,1-naphthalenecarboxylic acid deriv.; Azinomycin B; Cardinophyllin;Carzinophilin; Carzinophilin A; Carzinophillin; Carzinophillin A; Carzinophyllin;NSC 20088
  • PSA 210.36000
  • LogP -0.01330

Carzinophilin A Chemical Properties

IUPAC Name:   N-[[(9Z)-7-[(1-acetylaziridin-2-yl)-hydroxymethyl]-9-(1,3-dioxobutan-2-ylidene)-3-hydroxy-2-methyl-4,11-dioxo-1,5,8-trioxa-10-azaspiro[5.5]undecan-2-yl]methyl]-3-methoxy-5-methylnaphthalene-1-carboxamide
Synonyms of Carzinophilin A (CAS NO.1403-29-8): Antibiotic from Streptomyces Sahachiroi ; BRN 5721373 ; Cardinophillin ; Cardinophyllin ; Carzinophyllin ; NSC 20088 ; Carzinophilin (8CI)(9CI
CAS NO: 1403-29-8 
Molecular Formula of Carzinophilin A (CAS NO.1403-29-8): C31H33N3O12 
Molecular Weight: 639.6066  
H bond acceptors: 15
H bond donors: 4
Freely Rotating Bonds: 10
Polar Surface Area: 167.29 Å2
Index of Refraction: 1.66
Molar Refractivity: 156.93 cm3
Molar Volume: 424.6 cm3
Surface Tension: 76.4 dyne/cm
Density of Carzinophilin A (CAS NO.1403-29-8): 1.5 g/cm3
Flash Point: 555.1 °C
Enthalpy of Vaporization: 151.91 kJ/mol
Boiling Point: 994.3 °C at 760 mmHg
Vapour Pressure: 0 mmHg at 25°C
Molecular Structure:

Carzinophilin A Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 15ug/kg (0.015mg/kg)   "Antibiotics: Origin, Nature, and Properties," Korzyoski, T., et al., eds., Washington, DC, American Soc. for Microbiology, 1978Vol. 2, Pg. 1356, 1978.
mouse LD50 unreported 150ug/kg (0.15mg/kg)   "Index of Antibiotics from Actinomycetes," Umezawa, H. et al., eds., Tokyo, Univ. of Tokyo Press, 1967Vol. -, Pg. 199, 1967.

Carzinophilin A Safety Profile

Deadly poison by intravenous route. Mutation data reported.

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