Product Name: Coriamyrtin
Synonyms of Coriamyrtin (CAS NO:2571-86-0) : Coriamyrtine ; Coriamyrtione ; Spiro(2,5-methano-7H-oxireno(3,4)cyclopent(1,2-d)oxepin-7,2'-oxiran)-3(2H)-one, hexahydro-1b-hydroxy-6a-methyl-8-(1-methylethenyl)-, (1aS-(1aalpha,1bbeta,2beta,5beta,6abeta,7beta,7aalpha,8S*))- (9CI)
InChI: InChI=1/C15H18O5/c1-6(2)8-7-4-13(3)14(5-18-14)10-11(20-10)15(13,17)9(8)12(16)19-7/h7-11,17H,1,4-5H2,2-3H3/t7-,8+,9+,10+,11-,13-,14+,15-/m0/s1
Classification Code :Drug / Therapeutic Agent ;Natural Product
CAS NO:2571-86-0
Molecular Formula:C15H18O5
Molecular Weight :278.3004
Molecular Structure :
EINECS: 244-880-6
Index of Refraction: 1.611
Surface Tension: 55.3 dyne/cm
Density: 1.43 g/cm3
Flash Point: 187.3 °C
Enthalpy of Vaporization: 86.59 kJ/mol
Boiling Point: 485.9 °C at 760 mmHg
Vapour Pressure: 1.76E-11 mmHg at 25°C
Melting point: 229 ~ 230°C
Solubility: Coriamyrtin (CAS NO:2571-86-0) is slightly soluble in water and anhydrous ethanol, soluble in hot ethanol.
Coriamyrtin (CAS NO:2571-86-0) has central excitatory effect.
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
cat | LDLo | unreported | 237ug/kg (0.237mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Journal of Pharmacology and Experimental Therapeutics. Vol. 57, Pg. 361, 1936. |
frog | LDLo | subcutaneous | 10mg/kg (10mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Journal of Pharmacology and Experimental Therapeutics. Vol. 57, Pg. 410, 1936. |
guinea pig | LDLo | subcutaneous | 2439ug/kg (2.439mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Journal of Pharmacology and Experimental Therapeutics. Vol. 57, Pg. 361, 1936. |
mouse | LD50 | intraperitoneal | 3mg/kg (3mg/kg) | Journal of Medicinal Chemistry. Vol. 11, Pg. 729, 1968. | |
mouse | LD50 | subcutaneous | 3234ug/kg (3.234mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 29, Pg. 2, 1940. |
mouse | LDLo | intravenous | 1mg/kg (1mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Journal of Pharmacology and Experimental Therapeutics. Vol. 57, Pg. 410, 1936. |
rabbit | LD50 | intravenous | 371ug/kg (0.371mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 29, Pg. 2, 1940. |
rabbit | LD50 | subcutaneous | 930ug/kg (0.93mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 29, Pg. 2, 1940. |
rat | LDLo | intravenous | 700ug/kg (0.7mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Journal of Pharmacology and Experimental Therapeutics. Vol. 57, Pg. 410, 1936. |
rat | LDLo | subcutaneous | 1mg/kg (1mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Journal of Pharmacology and Experimental Therapeutics. Vol. 57, Pg. 410, 1936. |
Poison by subcutaneous, intravenous, intraperitoneal, and possibly other routes. When Coriamyrtin (CAS NO:2571-86-0) is heated to decomposition, it emits acrid smoke and fumes.
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