Cycloguanil hydrochloride supplier

Name
Cycloguanil Hydrochloride
EINECS
CAS No. 152-53-4
Article Data4
CAS DataBase
Density g/cm³
Solubility
Melting Point 210-2150C
Formula C11H14 Cl N5 . Cl H
Boiling Point 400.7°Cat760mmHg
Molecular Weight 288.18
Flash Point 196.1°C
Transport Information
Appearance
Safety Poison by subcutaneous, intravenous, and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NO_x and Cl⁻.
Risk Codes
Molecular Structure
Hazard Symbols
Synonyms 1,3,5-Triazine-2,4-diamine,1-(4-chlorophenyl)-1,6-dihydro-6,6-dimethyl-, monohydrochloride (9CI);s-Triazine, 4,6-diamino-1-(p-chlorophenyl)-1,2-dihydro-2,2-dimethyl-,hydrochloride (6CI); s-Triazine,4,6-diamino-1-(p-chlorophenyl)-1,2-dihydro-2,2-dimethyl-, monohydrochloride(8CI); 1-(4-Chlorophenyl)-1,6-dihydro-6,6-dimethyl-1,3,5-triazine-2,4-diaminemonohydrochloride; BN 2410; Chlorcycloguanil; Chloroguanide triazinehydrochloride; Cycloguanil hydrochloride; NSC 3074
PSA 80.00000
LogP 2.66430

Synthetic route

: 4022-81-5, 55307-40-9
1-(4-chlorophenyl)biguanide hydrochloride

: 67-64-1
acetone

: 152-53-4
cycloguanil hydrochloride

Conditions

Conditions	Yield
With hydrogenchloride; Triethyl orthoacetate In methanol at 20℃;	69%

: 106-47-8
4-chloro-aniline

: 127099-85-8, 780722-26-1
N-Cyanoguanidine

: 67-64-1
acetone

: 152-53-4
cycloguanil hydrochloride

Conditions

Conditions	Yield
With hydrogenchloride Cyclocondensation;	62%
With hydrogenchloride In water Reflux;

...Expand

: 127099-85-8, 780722-26-1
dicyandiamide

: 106-47-8
4-chloro-aniline

: 67-64-1
acetone

: 152-53-4
cycloguanil hydrochloride

Conditions

Conditions	Yield
With hydrogenchloride for 24h; Heating;	31%

...Expand

: 152-53-4
cycloguanil hydrochloride

: 5405-65-2
N2-(4-chloro-phenyl)-6,6-dimethyl-1,6-dihydro-1,3,5-triazine-2,4-diamine

Conditions

Conditions	Yield
In pyridine; ethanol for 12h; Heating;	95%
With sodium hydroxide In ethanol; water for 1h; pH=11; Dimroth rearrangement; Reflux;	2.11 g

Cycloguanil hydrochloride Chemical Properties

Empirical Formula: C₁₁H₁₅Cl₂N₅
Molecular Weight: 288.1763
Flash Point: 196.1 °C
Enthalpy of Vaporization: 65.16 kJ/mol
Boiling Point: 400.7 °C at 760 mmHg
Vapour Pressure: 1.25E-06 mmHg at 25 °C
Melting point: 210-215 °C
Appearance: Crystalline solid
Product categories of Cycloguanil hydrochloride (CAS NO.152-53-4): Aromatics Compounds;Aromatics;Nucleotides;Bases & Related Reagents;Pharmaceuticals;Isotope Labeled Compounds;Heterocycles;Intermediates & Fine Chemicals
Structure of Cycloguanil hydrochloride (CAS NO.152-53-4):

Cycloguanil hydrochloride Uses

Cycloguanil hydrochloride (CAS NO.152-53-4) has been used for labelled antimalarial drug.

Cycloguanil hydrochloride Toxicity Data With Reference

1.	ipr-mus LD50:54 mg/kg	TXAPA9 Toxicology and Applied Pharmacology. 18 (1971),487.
2.	scu-mus LD50:220 mg/kg	ATMPA2 Annals of Tropical Medicine and Parasitology. 74 (1980),393.
3.	ivn-dog LDLo:24 mg/kg	TXAPA9 Toxicology and Applied Pharmacology. 18 (1971),487.

Cycloguanil hydrochloride Safety Profile

Poison by subcutaneous, intravenous, and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NO_x and Cl⁻.

Cycloguanil hydrochloride Specification

Cycloguanil hydrochloride ,its cas register number is 152-53-4. It also can be called Chlorcycloguanil ; s-Triazine, 4,6-diamino-1-(p-chlorophenyl)-1,2-dihydro-2,2-dimethyl-, monohydrochloride or 1-(4-chlorophenyl)-6,6-dimethyl-1,6-dihydro-1,3,5-triazine-2,4-diamine hydrochloride .

Product Name

Cycloguanil Hydrochloride

Synthetic route

Cycloguanil hydrochloride Chemical Properties

Cycloguanil hydrochloride Uses

Cycloguanil hydrochloride Toxicity Data With Reference

Cycloguanil hydrochloride Safety Profile

Cycloguanil hydrochloride Specification

Related Products

Hot Products