-
Name
dexamethasone 21-(sodium sulphate)
- EINECS
- CAS No. 466-11-5
- Density g/cm3
- Solubility
- Melting Point
- Formula C22H29FO8S•Na
- Boiling Point °Cat760mmHg
- Molecular Weight 495.56
- Flash Point °C
- Transport Information
- Appearance
- Safety Moderately toxic by intraperitoneal and subcutaneous routes. A steroid. When heated to decomposition it emits toxic fumes of F−, SOx, and Na2O.
- Risk Codes
-
Molecular Structure
- Hazard Symbols
- Synonyms
- PSA
- LogP
DEXAMETHASONE SODIUM SULFATE Chemical Properties
Product Name: Dexamethasone sodium sulfate (CAS NO.466-11-5)
Molecular Formula: C22H28FNaO8S
Molecular Weight: 494.5061 g/mol
Mol File: 466-11-5.mol
Einecs: 207-374-6
H-Bond Donor: 2
H-Bond Acceptor: 9
Rotatable Bond Count: 4
Tautomer Count: 6
Topological Polar Surface Area: 141
Heavy Atom Count: 33
Formal Charge: 0
Complexity: 1040
Defined Atom StereoCenter Count: 8
Covalently-Bonded Unit Count: 2
DEXAMETHASONE SODIUM SULFATE Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intraperitoneal | 1660mg/kg (1660mg/kg) | Drugs in Japan Vol. 6, Pg. 477, 1982. | |
| mouse | LD50 | oral | > 7500mg/kg (7500mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) GASTROINTESTINAL: OTHER CHANGES LIVER: OTHER CHANGES | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 5, Pg. 6, 1974. |
| mouse | LD50 | subcutaneous | 2020mg/kg (2020mg/kg) | Drugs in Japan Vol. 6, Pg. 477, 1982. | |
| rat | LD50 | intramuscular | > 400mg/kg (400mg/kg) | Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 21, Pg. 2117, 1979. | |
| rat | LD50 | intraperitoneal | 2180mg/kg (2180mg/kg) | Drugs in Japan Vol. 6, Pg. 477, 1982. | |
| rat | LD50 | intravenous | 1gm/kg (1000mg/kg) | Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 21, Pg. 2117, 1979. | |
| rat | LD50 | oral | > 7500mg/kg (7500mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) GASTROINTESTINAL: OTHER CHANGES LIVER: OTHER CHANGES | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 5, Pg. 6, 1974. |
| rat | LD50 | subcutaneous | 3450mg/kg (3450mg/kg) | Drugs in Japan Vol. 6, Pg. 477, 1982. |
DEXAMETHASONE SODIUM SULFATE Safety Profile
Moderately toxic by intraperitoneal and subcutaneous routes. A steroid. When heated to decomposition it emits toxic fumes of F−, SOx, and Na2O.
DEXAMETHASONE SODIUM SULFATE Specification
Dexamethasone sodium sulfate ,its CAS NO. is 466-11-5,the synonyms is Dexamethasone 21-(sodium sulphate) ; 9-Fluoro-11β,17-dihydroxy-16α-methyl-21-sodiosulfooxypregna-1,4-diene-3,20-dione .
Related Products
- Dexamethasone
- Dexamethasone 17,21-dipropionate
- Dexamethasone 21-(sodium hydrogen phosphate)
- Dexamethasone 21-phenylpropionate
- Dexamethasone 21-phosphate disodium salt
- Dexamethasone acetate monohydrate
- DEXAMETHASONE ISONICOTINATE
- Dexamethasone palmitate
- DEXAMETHASONE SODIUM SULFATE
- Dexamethasone trimethyl acetate
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- 4664-00-0
- 4664-01-1
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- 4664-55-5
- 4664-8-8
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