Doloxene supplier | CasNO.17140-78-2

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Name
PROPOXYPHENE NAPSYLATE
EINECS 241-205-7
CAS No. 17140-78-2
Density g/cm³
Solubility 1.4g/L(22 oC)
Melting Point
Formula C₁₀H₈O₃S•C₂₂H₂₉NO₂
Boiling Point 444°Cat760mmHg
Molecular Weight 547.76
Flash Point 130.6°C
Transport Information
Appearance
Safety Poison by ingestion. Human systemic effects by ingestion: somnolence, vascular changes. Experimental reproductive effects. When heated to decomposition it emits very toxic fumes of NO_x and SO_x. See also SULFONATES.
Risk Codes
Molecular Structure
Hazard Symbols
Synonyms Darvon N;Propoxyphene napsylate;2-Naphthalenesulfonic acid,compd. with (1S,2R)-3-(dimethylamino)-2-methyl-1- phenyl-1-(phenylmethyl)propyl propanoate (1:1);DARVON-N;PROPOXYPHENE N;PROPOXYPHENE-2-NAPHTHALENESULFONATE;4-(DIMETHYLAMINO)-3-METHYL-1,2-DIPHENYL-2-BUTANOL PROPIONATE-2-NAPHTHALENESULFONATE;
PSA 92.29000
LogP 7.44280

Doloxene Chemical Properties

IUPAC Name: [(2S,3R)-4-(Dimethylamino)-3-methyl-1,2-diphenylbutan-2-yl] propanoate; naphthalene-2-sulfonic acid
Synonyms of Doloxene (CAS NO.17140-78-2) : (+)- Propoxyphene napsylate ; 2-Butanol, 4-(dimethylamino)-3-methyl-1,2-diphenyl-, propionate, 2-naphthalenesulfonate ; Darvon N ; Dextropropoxyphene Napsylate ; Propoxyphene 2-naphthalenesulfonate ; 2-Naphthalenesulfonic acid, compd. with (+)-alpha-(2-dimethylamino)-1-methylethyl-alpha-phenylphenethyl propionate (1:1) ; Benzeneethanol, alpha-(2-(dimethylamino)-1-methylethyl)-alpha-phenyl-, propanoate (ester), (1S,2R)-, 2-naphthalenesulfonate (salt)
InChI:InChI=1/C22H29NO2.C10H8O3S/c1-5-21(24)25-22(18(2)17-23(3)4,20-14-10-7-11-15-20)16-19-12-8-6-9-13-19;11-14(12,13)10-6-5-8-3-1-2-4-9(8)7-10/h6-15,18H,5,16-17H2,1-4H3;1-7H,(H,11,12,13)/t18-,22+;/m1./s1
CAS NO:17140-78-2
Molecular Formula:C₃₂H₃₇NO₅S
Molecular Weight :547.7049
Molecular Structure :
Flash Point: 130.6 °C
Enthalpy of Vaporization: 70.17 kJ/mol
Boiling Point: 444 °C at 760 mmHg
Vapour Pressure: 4.43E-08 mmHg at 25°C

Doloxene Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
man	TDLo	oral	129mg/kg (129mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) VASCULAR: OTHER CHANGES	Journal of Toxicology, Clinical Toxicology. Vol. 23, Pg. 347, 1985.
mouse	LD50	oral	915mg/kg (915mg/kg)		Toxicology and Applied Pharmacology. Vol. 19, Pg. 445, 1971.
rabbit	LDLo	oral	183mg/kg (183mg/kg)		Toxicology and Applied Pharmacology. Vol. 19, Pg. 445, 1971.
rat	LD50	oral	647mg/kg (647mg/kg)		Toxicology and Applied Pharmacology. Vol. 19, Pg. 445, 1971.

Doloxene Safety Profile

Poison by ingestion. Human systemic effects by ingestion: somnolence, vascular changes. Experimental reproductive effects. When Doloxene (CAS NO.17140-78-2) is heated to decomposition ,it emits very toxic fumes of NO_x and SO_x. See also SULFONATES.

Product Name

PROPOXYPHENE NAPSYLATE

Doloxene Chemical Properties

Doloxene Toxicity Data With Reference

Doloxene Safety Profile

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