Econazole supplier | CasNO.27220-47-9

Name
Econazole
EINECS 248-341-6
CAS No. 27220-47-9
Article Data3
CAS DataBase
Density 1.33 g/cm³
Solubility 0.37g/L(ambient temperature)
Melting Point 86.8 °C
Formula C₁₈H₁₅Cl₃N₂O
Boiling Point 533.8 °C at 760 mmHg
Molecular Weight 381.689
Flash Point 276.6 °C
Transport Information
Appearance
Safety 24/25-36/37/39
Risk Codes 36/37/38
Molecular Structure
Hazard Symbols Xi
Synonyms Imidazole,1-[2,4-dichloro-b-[(p-chlorobenzyl)oxy]phenethyl]-(8CI);1-[2,4-Dichloro-b-[(p-chlorobenzyl)oxy]phenethyl]imidazole;NSC 187789;
PSA 27.05000
LogP 5.80140

Econazole Chemical Properties

Molecular Formula: C₁₈H₁₅Cl₃N₂O
Formula Weight: 381.68
mp: 86.8^°C
State: Solid
Predicted WATER Solubility: 1.48e-03 mg/mL

Econazole Uses

Econazole is the first generation of products Imidazole antifungal agents. It is used topically in dermatomycoses also orally and parenterally.

Econazole Production

10.3 in the α-(2,4-dichlorophenyl)-imidazole-1-ethanol and 2.1 in Sodium hydride 50 anhydrous tetrahydrofuran the slurry mixing returning 2h, when hydrogen reaction after successive accession 60 dimethyl formamide and 8-chloro-benzyl chloride to return 2h. Tetrahydrofuran pressure steam addition, the residues dumped into the WATER with Benzene extraction, extracts from decompression Benzene, in econazole in the free base, and then concentrated nitric acid, generating econazole nitrate.

Econazole Toxicity Data With Reference

Overdosage of econazole in humans has not been reported to date. In mice, rats guinea pigs and dogs, the oral LD₅₀ values were found to be 462, 668, 272, and > 160 mg/kg, respectively.

Econazole Safety Profile

Hazard Codes : Xi
Risk Statements : 36/37/38
Safety Statements : 24/25-36/37/39

Product Name

Econazole

Econazole Chemical Properties

Econazole Uses

Econazole Production

Econazole Toxicity Data With Reference

Econazole Safety Profile

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